Last update 16 May 2024

Oxaliplatin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Diaminocyclohexane Oxalatoplatinum, GSOX, L-OHP
+ [35]
Target
Mechanism
DNA inhibitors(DNA inhibitors), DNA cross linking agents, DNA synthesis inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US), Accelerated Approval (US)
Login to view First Approval Timeline

Structure

Molecular FormulaC8H14N2O4Pt
InChIKeyZROHGHOFXNOHSO-BNTLRKBRSA-L
CAS Registry61825-94-3

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Small intestine carcinoma
JP
21 Sep 2018
Colorectal Cancer
JP
20 Aug 2009
Rectal Cancer
US
09 Aug 2002
Neoplasms
CN
01 Jan 2000
Colonic Cancer
FR
01 Jan 1996
Pancreatic Cancer
FR
01 Jan 1996
Stomach Cancer
FR
01 Jan 1996
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Colonic CancerDiscovery
GB
01 Oct 1998
Colonic CancerDiscovery
DK
01 Oct 1998
Colonic CancerDiscovery
NO
01 Oct 1998
Colonic CancerDiscovery
HU
01 Oct 1998
Colonic CancerDiscovery
SG
01 Oct 1998
Colonic CancerDiscovery
AT
01 Oct 1998
Colonic CancerDiscovery
IT
01 Oct 1998
Colonic CancerDiscovery
PT
01 Oct 1998
Colonic CancerDiscovery
GR
01 Oct 1998
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
770
irinotecan liposome + oxaliplatin+5-fluorouracial/leucovorin
(CA19-9 decrease)
(vfpqkofrkw) = hiturrngyr rdlczbrfuh (jzlmgimcjj )
Positive
18 Jan 2024
irinotecan liposome + oxaliplatin+5-fluorouracial/leucovorin
(without CA19-9 decrease)
(vfpqkofrkw) = kxuexkbltl rdlczbrfuh (jzlmgimcjj )
Not Applicable
38
(ktmspkrzge) = hbujcytfum ijgabzezyn (qojxtcnqfn, 1.0 ~ 28)
Negative
18 Jan 2024
AACR2024
ManualManual
Phase 1/2
28
(gjkqxhcrph) = ccnketatfa ratgypzipv (mmutxmcsas )
Positive
05 Apr 2024
Phase 2
34
(gobdovjeis) = phuwwtjaky qawnaoyupn (mhmddrighx )
Positive
18 Jan 2024
Not Applicable
30
(riujdyggdz) = nbnnrwspij xrakrrwjfx (qmnuvxhgom, 0.13 ~ 0.35)
Positive
18 Jan 2024
Phase 3
324
modified CAPOX or modified FDocetaxeldocetaxeloxaliplatincapecitabine
(zhogiqmcsc) = twgtukdekt zgopnmamdy (eopaxaocfk, 9.2-10.9)
Negative
18 Jan 2024
(zhogiqmcsc) = wubeazoiuz zgopnmamdy (eopaxaocfk, 7.3-10.5)
Phase 2
51
(uorcceffwu) = mxcuwuqnbx djsqadfgkg (kabbakvnnq )
Positive
18 Jan 2024
Phase 2
30
(svsnfyhwov) = ndjifhzxsd cttwapubsf (yeewccdyuy, 50.1 ~ 80.7)
Positive
18 Jan 2024
Phase 2
60
(evybsvpcfi) = tentpfzuvw sqjdwdxszv (yzbmdjpobt )
Positive
18 Jan 2024
Phase 2
Rectal Cancer
Neoadjuvant
30
(alcysgaeax) = ljrtzciwkj rjxwxaxluh (imbsfyvwlh, 14.0 ~ 50.8)
Positive
18 Jan 2024
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free