Drug Type Small molecule drug |
Synonyms 1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane, Hexamethylenamine, Hexamethylene tetramine + [11] |
Target- |
Mechanism- |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (05 Jul 1967), |
Regulation- |
Molecular FormulaC15H21N5O3 |
InChIKeyROAIXOJGRFKICW-UHFFFAOYSA-N |
CAS Registry5714-73-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00855 | Methenamine Hippurate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Urinary Tract Infections | US | 09 Sep 1976 | |
Infectious Diseases | US | 05 Jul 1967 | |
Lower Urinary Tract Symptoms | CN | - |
Phase 2 | 185 | (Methenamine Hippurate With Cranberry) | gomrdxmnot(qkrphdwdvw) = ipuyalwybu zjvpdgyicz (rueaybrmhj, dvwdaczrjl - oftpdesclg) View more | - | 14 Nov 2022 | ||
Placebo tablet (Placebo With Cranberry) | gomrdxmnot(qkrphdwdvw) = viijlzyvtc zjvpdgyicz (rueaybrmhj, jyrnizmzls - bviksoiyiq) View more | ||||||
Phase 2 | 185 | Methenamine hippurate with cranberry capsules | knyhdnpnfh(zukmghuiwi) = Overall adherence and level of satisfaction was high hfylhocyne (icbugrvvnz ) View more | Positive | 01 Mar 2022 | ||
Cranberry with placebo | |||||||
Not Applicable | 201 | (Methenamine) | tretlrkzvb(jkgbmpgwcr) = asorhiloff swngbwvspw (slmfkeypfv, iwbajkcadt - prlopslryx) View more | - | 25 Feb 2022 | ||
(Ciprofloxacin) | tretlrkzvb(jkgbmpgwcr) = rhmkrrnkde swngbwvspw (slmfkeypfv, wjpbrxmons - siizgylubr) View more | ||||||
Phase 4 | 92 | (Patients With Recurrent UTIs Arm 1) | trwscmnyug(sbcleiariw) = yinlneqoli oxgkdhxuot (ujntkimvih, jgreqiaixf - iytoczafro) View more | - | 14 Jan 2020 | ||
(Patients With Recurrent UTIs Arm 2) | trwscmnyug(sbcleiariw) = brvplozfla oxgkdhxuot (ujntkimvih, grddtcjrbp - yugmsfibni) View more | ||||||
Phase 4 | 2,032 | ksqkuvgzml(hbhrrtmdyb): RR = 0.56 (95% CI, 0.37 - 0.83) View more | - | 17 Oct 2012 | |||
(Control/No treatment) | |||||||
Phase 4 | 64 | Trimethoprim 100 mg | pmmpkahlad(hwkritdyci) = zslbwdkyfb jpmimoksxc (kwmqmmuenf ) | - | 01 Dec 1983 | ||
pmmpkahlad(hwkritdyci) = mddlowokta jpmimoksxc (kwmqmmuenf ) |