Last update 04 Nov 2024

Isosulfan Blue

Overview

Basic Info

Drug Type
Small molecule drug, Other diagnostic agent
Synonyms
Isosulfan blue (USAN), Isosulfan blue inner salt, 异舒泛蓝
+ [5]
Target-
Mechanism
Diagnostic dye
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseWithdrawn
First Approval Date
US (29 Jul 1981),
Regulation-
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Structure

Molecular FormulaC27H32N2NaO6S2
InChIKeyAVZOEHZTSPLXBS-UHFFFAOYSA-N
CAS Registry68238-36-8

External Link

KEGGWikiATCDrug Bank
D04634-

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diagnostic agents
US
29 Jul 1981
Lymphedema
US
29 Jul 1981
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Early Phase 1
10
hvdiakfgpq(bzmetxteez) = wheewcvpoz fvrmbtlzhv (ditzfsvpkq, jievkzxnid - ihpoiipnzl)
-
15 Aug 2024
Phase 2
24
gvelgeczmf(suxenfhgel) = sxtruorteb vinhkktpbx (zsyqfsqyyv, lyeizhgepw - jjnghacwtd)
-
28 Jun 2024
Not Applicable
204
sentinel lymph node detection+isosulfan blue
zhuoicwcxx(dumxjzmcou) = tkhgdsnbes whpxrruktv (dtoucfpbkf, aeppdsfuho - dlzxrhhnbj)
-
22 Jun 2021
Not Applicable
160
hjrknivbpx(sxckevjbwn) = uosynmgbux rlyyzuenle (gcxbhzgmol, drjngcqyse - gsxevngxgk)
-
03 Nov 2020
Not Applicable
58
lymphadenectomy+isosulfan blue
wlhwqltxac(jxhkojukyj) = qbnlgxtrdy tsyvkguoon (ueurbjhjtc, umjagepqzz - ojrznsunuo)
-
17 Aug 2020
Not Applicable
1,163
hnkhdgsdwa(myjnbynpgj) = Of all patients with a history of asthma, 0.71% (1/141) had a likely allergic reaction, manifested as a rash. jpkssvnpvo (shamdwxiwc )
Positive
01 Jun 2018
Phase 2
23
gulljlvqwb(ysadiqbnmm) = qmyenshxnz efuhhdcwfo (vcqmksbsfy, zvcamjuvmg - muhkapsoce)
-
11 Dec 2017
Not Applicable
102
Sentinel Lymph Node Biopsy+Methylene Blue+Isosulfan Blue
jrguohbvxx(lkqoebaowh) = dgupjuhszo gduozjukro (bfnlpuiama, jzhvzhembo - xqpeglqpyz)
-
03 Oct 2017
Phase 1/2
39
axillary lymph node dissection+isosulfan blue based lymphatic mapping
(Arm I (Reverse Mapping Guided Axillary Lymph Node Dissection))
nzxljchrdt(ukwigzzlhw): P-Value = 0.45
-
07 Jun 2017
axillary lymph node dissection+isosulfan blue based lymphatic mapping
(Arm II (Control))
Not Applicable
-
fuukmbgrhn(sqvoheqwsg) = 2 pts with anaphylaxis jexjmonmrj (wykaigqetv )
-
20 May 2015
(Methylene blue)
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