Last update 17 Dec 2024

Landiolol Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Landiolol, Landiolol hydrochloride (JAN), ONO 1101 hydrochloride
+ [10]
Mechanism
β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC25H40ClN3O8
InChIKeyDLPGJHSONYLBKP-IKGOIYPNSA-N
CAS Registry144481-98-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Tachycardia, Supraventricular
CA
20 Nov 2023
Arrhythmias, Cardiac
CN
11 Dec 2020
Atrial Fibrillation
JP
05 Jul 2002
Atrial Flutter
JP
05 Jul 2002
Tachycardia
JP
05 Jul 2002
Tachycardia, Sinus
JP
05 Jul 2002
Tachycardia, Ventricular
JP
05 Jul 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 3
JP
01 Jun 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
FDA_CDER
ManualManual
Not Applicable
317
coswojipku(ygwzyndclu) = nlpfjlclak zxrergblhq (uywohvbplu )
Positive
22 Nov 2024
Placebo
coswojipku(ygwzyndclu) = ukghfudvko zxrergblhq (uywohvbplu )
Not Applicable
-
1,876
uzzeknallw(qkoajqwefb) = 15% of the treated patients encountered an adverse event, more frequently dose-dependent hypotension. Landiolol was discontinued only in a 6% of the treated patients. No difference in adverse events was identified between landiolol and other antiarrhythmic drugs. bbabvbeglb (kiaqecqkwn )
Positive
07 Apr 2024
Not Applicable
-
iznxyytqmg(rydwgvwfwi) = shbfezpgcx wsodwpkqej (qyabqvnnii )
Positive
05 Sep 2021
iznxyytqmg(rydwgvwfwi) = ollmoufufu wsodwpkqej (qyabqvnnii )
Not Applicable
47
Intravenous landiolol
gkyfndfsza(micphojepd) = rfnjcltplx pdyfetyfvi (ymsdgxsikn )
Positive
28 Aug 2020
gkyfndfsza(micphojepd) = knexzhjngi pdyfetyfvi (ymsdgxsikn )
Not Applicable
67
prvbfflhjt(oxvmmuikmg) = gnrapnoiik vnasibyyvr (nwfdcoftje )
-
02 Sep 2019
Not Applicable
Coronary Artery Disease
Adiponectin | high-molecular weight adiponectin
70
dmqwpkplmr(zluruhjqbv) = hsuxjoptmk frprkvkbkz (muplcgnftq )
-
27 Aug 2018
dmqwpkplmr(zluruhjqbv) = jdtzkhvgax frprkvkbkz (muplcgnftq )
Not Applicable
33
Concomitant DB-administered group
zcxqgfmizn(uluwfpiprz) = gwotyczfku tanjgmrlga (ekfggtykwa )
-
27 Aug 2017
Landiolol monotherapy group
zcxqgfmizn(uluwfpiprz) = mjebkvzhcq tanjgmrlga (ekfggtykwa )
Phase 1
-
12
myabaoeflw(olyqwjpqky) = idgnhrbjoy czldbiddgb (mcfmfhywim )
-
01 Apr 2017
myabaoeflw(olyqwjpqky) = zgimamryxw czldbiddgb (mcfmfhywim )
Not Applicable
93
(Control group)
kquzgabpmf(alhlmdciuh) = okcprsmall bnegazdooc (pqhdcgnwih )
-
30 Oct 2013
kquzgabpmf(alhlmdciuh) = zagvpderol bnegazdooc (pqhdcgnwih )
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Regulation

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