Last update 31 Jul 2025

Landiolol Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Landiolol, Landiolol hydrochloride (JAN), ONO 1101 hydrochloride
+ [10]
Action
antagonists
Mechanism
β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC25H40ClN3O8
InChIKeyDLPGJHSONYLBKP-IKGOIYPNSA-N
CAS Registry144481-98-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Tachycardia, Supraventricular
Canada
20 Nov 2023
Arrhythmias, Cardiac
China
11 Dec 2020
Atrial Fibrillation
Japan
05 Jul 2002
Atrial Flutter
Japan
05 Jul 2002
Tachycardia
Japan
05 Jul 2002
Tachycardia, Sinus
Japan
05 Jul 2002
Tachycardia, Ventricular
Japan
05 Jul 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 3
Japan
01 Jun 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
FDA_CDER
ManualManual
Not Applicable
317
fvvelibytd(wwokuqtdwl) = knhcchvowm iwjidxiduu (hexqdjkbxm )
Positive
22 Nov 2024
Placebo
fvvelibytd(wwokuqtdwl) = uvjitvkfjq iwjidxiduu (hexqdjkbxm )
Phase 3
404
Surgery combined with continuous infusion of landiolol
gplvaqonjb(zicqrmxlcf) = ipvjaiovaf dnnaeqkhcj (mlsicelhgj, 71.8 - 83.8)
Negative
14 Sep 2024
landiolol
(Surgery alone)
gplvaqonjb(zicqrmxlcf) = jhrgheecee dnnaeqkhcj (mlsicelhgj, 70.5 - 82.5)
Phase 2
183
Landiolol hydrochloride 0.06-mg/kg
nqsyehppmr(dwsmtuldwk) = No adverse events or reactions occurred at an incidence of 5 % or greater, confirming the safety of landiolol hydrochloride ldersatkpi (jcnwlovkcr )
-
01 Jun 2013
Landiolol hydrochloride 0.125-mg/kg
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Approval

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Regulation

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