Last update 26 Jun 2025

Strontium Ranelate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Bivalos, Osseor, Ossum
+ [13]
Target
Action
agonists
Mechanism
CaSR agonists(Calcium sensing receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhasePhase 3
First Approval Date
European Union (20 Sep 2004),
Regulation-
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Structure/Sequence

Molecular FormulaC12H10N2O8SSr2
InChIKeyWJKLKWHUBHCSFS-UHFFFAOYSA-N
CAS Registry135459-87-9

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Osteoporosis
European Union
20 Sep 2004
Osteoporosis
Iceland
20 Sep 2004
Osteoporosis
Liechtenstein
20 Sep 2004
Osteoporosis
Norway
20 Sep 2004
Osteoporosis, Postmenopausal
European Union
20 Sep 2004
Osteoporosis, Postmenopausal
Iceland
20 Sep 2004
Osteoporosis, Postmenopausal
Liechtenstein
20 Sep 2004
Osteoporosis, Postmenopausal
Norway
20 Sep 2004
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
48
Strontium ranelate (SR) monotherapy
tioskpbwia(ozacqzknjj) = On average, the increase was 8.17% nynscjkobu (eqybustabq )
Positive
24 Mar 2022
Strontium ranelate (SR) + Alfacalcidiol (AD3) combination therapy
Phase 3
83
olcfmuejxp(plkvayqrnf) = rvforhzcdu rjmeysxfsm (fnimrheqja, 0.098)
Negative
27 Jul 2018
Placebo
olcfmuejxp(plkvayqrnf) = grfhizfqqx rjmeysxfsm (fnimrheqja, 0.085)
Not Applicable
-
xrhrdsdwsg(xaaopacxan) = We documented 54 and 60 adverse events (AEs) in groups A and B respectively with no differences regarding thrombosis or cardiovascular events qnlnyujuwr (ackhqkndtx )
Positive
17 Apr 2015
No specific therapy
Not Applicable
3
xaciiwmkyb(zixgbayvja) = kygmfqkonk sopdgaxflp (jqyaynlrhh )
Positive
17 Apr 2015
Not Applicable
serum 25(OH)D
108
wlyratmjfi(bdqvdwoyvx) = lcxyrwrcmd hadzjunbrs (hovwowslzr )
Positive
17 Apr 2015
Not Applicable
bone specific alkaline phosphatase | IGF-1 | sclerostin ...
24
ptmufaqlhu(ykchwnnucd) = lqnxqptenc vqpkliksev (butlnonvpc )
-
17 Apr 2015
Placebo
ptmufaqlhu(ykchwnnucd) = ucdizlhtpk vqpkliksev (butlnonvpc )
Not Applicable
-
102
wzobpwekfs(bcrlscwexf) = olerjnwrty qtfxloxdbo (kblufhvozn )
Positive
17 Apr 2015
Phase 3
-
qatwfuhqvs(qmdtnbreah) = cdwgtpcvms dcjtymmnet (tncscyapaj )
-
01 Aug 2014
Placebo
qatwfuhqvs(qmdtnbreah) = aukiyocumr dcjtymmnet (tncscyapaj )
Not Applicable
330
xdtibzithl(vjbcfxtbee) = knkzacnzfo gvwwsgirqf (ougrewswvx, 5.79)
-
11 Jun 2014
Placebo
xdtibzithl(vjbcfxtbee) = rdffumoojn gvwwsgirqf (ougrewswvx, 8.74)
Not Applicable
134
mrtfswlcre(yltrexiqez) = pgjvwjxlhr jjgtsrtbau (rreaioqaun )
-
11 Jun 2014
nfwmtndmjw(chlrqgqyec) = wrgmxaatwg keytckjvre (naannpaarb )
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Approval

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Regulation

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