Last update 01 Jul 2024

Polmacoxib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acelex, Polmacoxib (USAN/INN), CG-100649
+ [3]
Target
Mechanism
COX-2 inhibitors(Cyclooxygenase-2 inhibitors)
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
KR (05 Feb 2015),
Regulation-
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Structure

Molecular FormulaC18H16FNO4S
InChIKeyIJWPAFMIFNSIGD-UHFFFAOYSA-N
CAS Registry301692-76-2

External Link

KEGGWikiATCDrug Bank
D10656Polmacoxib

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Osteoarthritis
KR
05 Feb 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, HipPhase 3
KR
01 Mar 2013
Primary osteoarthritis of knee NOSPhase 3
KR
01 Mar 2013
NeuralgiaPhase 1
US
30 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
28
(CG100649 6mg + Ketoconazole 400 mg)
pdtqmnrvva(cyaxqjxayj) = siehldpftm tfctcopjnp (wemagpdtko, ehthpzdest - xczlmlqswp)
-
03 Jan 2024
(CG100649 6mg Single Dosing)
pdtqmnrvva(cyaxqjxayj) = ageoahduuq tfctcopjnp (wemagpdtko, rbwbiidmxo - lcigtsbavh)
Phase 3
362
Placebo
(Placebo)
xzozsyaqcc(xjqgunayrj) = ysekspoczu jsrmznccax (tipxwoyngn, ufblkhwoiz - cnisxgzats)
-
15 Feb 2023
(CG100649)
volxxtqrsg(olgyyspman) = fwikrcqxdp rjfueclrrz (zbyrbdqmup, nigzbmpbeq - covwazoiep)
Phase 2
125
apnzshecno(jvbmhozklr) = rkehwoenqw vlwbjkbrwi (gctbhaqyne, eyivznhrah - pxcagouvdh)
-
09 Feb 2023
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Approval

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Regulation

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