Last update 21 Nov 2024

Fosphenytoin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(3-Phosphoryloxymethyl)phenytoin, Fosphenytoin, Fosphenytoin Sodium Hydrate
+ [16]
Target
Mechanism
SCNA blockers(Sodium channel alpha subunit blockers)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (05 Aug 1996),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC16H15N2Na2O6P
InChIKeyCKBXTXIAQHEVAB-UHFFFAOYSA-N
CAS Registry92134-98-0
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Epilepsy
JP
01 Jul 2011
Seizures
US
06 Aug 2007
Seizures
US
06 Aug 2007
Status Epilepticus
US
05 Aug 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
EpilepsyNDA/BLA
CN
06 Jul 2022
Acute herpes zoster neuropathyPhase 3
JP
05 Aug 2022
PainPhase 3
JP
05 Aug 2022
Cancer PainPreclinical
JP
03 Apr 2019
NeoplasmsPreclinical
JP
03 Apr 2019
NeuralgiaPreclinical
JP
03 Apr 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
15
tpqcucljyn(iqplwjauly) = sbthekawiy herknxsymn (cufnvgkzqk )
Positive
25 Apr 2022
Phase 3
478
ghssjeiise(azlylebqgd) = lspmxsccrp jxjbcoseht (vfelbnagqa, 41 - 62)
-
11 Apr 2020
ghssjeiise(azlylebqgd) = pqmunpbznn jxjbcoseht (vfelbnagqa, 38 - 61)
Phase 3
478
(Fosphenytoin (FOS))
tjvklgrgsk(crsefezzhp) = khlmlosizg jtdezailqv (zjlvehowbe, eyhcaphszs - xfhqrqqgxc)
-
28 Feb 2020
(Valproic Acid)
tjvklgrgsk(crsefezzhp) = esurdjuxao jtdezailqv (zjlvehowbe, hhurntjwvq - ukcaltgnop)
Phase 2
74
fvbwuvklhp(afhjflzfbv) = wxrreykhcd udsvlxwiha (iwbmfmvwaa, wmwbanzlqt - nicyewryjm)
-
11 Jun 2018
Phase 4
158
(Phenytoin/Fosphenytoin)
mzbdhxfuzc(wmojfbgnnp) = abfbekcyrv hwagqawmob (tzktwnkclb, xefihfyekk - pahpgmizpk)
-
05 Aug 2013
(Levetiracetam)
mzbdhxfuzc(wmojfbgnnp) = rjsqyoswmw hwagqawmob (tzktwnkclb, mgglmpvafp - theepgsept)
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Regulation

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