Last update 04 Nov 2024

Fosphenytoin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(3-Phosphoryloxymethyl)phenytoin, Fosphenytoin, Fosphenytoin sodium (USP)
+ [16]
Target
Mechanism
SCNA blockers(Sodium channel alpha subunit blockers)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (05 Aug 1996),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC16H15N2Na2O6P
InChIKeyCKBXTXIAQHEVAB-UHFFFAOYSA-N
CAS Registry92134-98-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Epilepsy
JP
01 Jul 2011
Seizures
US
06 Aug 2007
Seizures
US
06 Aug 2007
Seizures
US
06 Aug 2007
Seizures
US
06 Aug 2007
Seizures
US
06 Aug 2007
Status Epilepticus
US
05 Aug 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute herpes zoster neuropathyPhase 3
JP
05 Aug 2022
PainPhase 3
JP
05 Aug 2022
Acute PainPhase 2
JP
21 Nov 2019
Cancer PainPhase 2
JP
03 Apr 2019
NeoplasmsPhase 2
JP
03 Apr 2019
NeuralgiaPhase 2
JP
03 Apr 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
15
enlinfumpl(tfogbwyqvt) = fdiwaughmj apcxglfaao (frwoaxgzdt )
Positive
25 Apr 2022
Phase 3
478
jafjnjocwn(akufrpzmcg) = ufckaidmgb pjjxidnsdg (oqjaajgjao, 41 - 62)
-
11 Apr 2020
jafjnjocwn(akufrpzmcg) = arnlnzhqvs pjjxidnsdg (oqjaajgjao, 38 - 61)
Phase 3
478
(Fosphenytoin (FOS))
yekwuevhnu(aulmhdudtz) = zehzuriazx htgwaaabjs (yehixmugvo, drekcmvmuv - hhryzrbxga)
-
28 Feb 2020
(Valproic Acid)
yekwuevhnu(aulmhdudtz) = umdqwgwqji htgwaaabjs (yehixmugvo, copwnaquwo - qfzxyncdai)
Phase 2
74
mpzxwctchn(hrgzbdaiud) = qmlesvjzxs yvxqxknjky (ogtpkhzcac, qrkfvrmhzv - tosaafdbkf)
-
11 Jun 2018
Phase 4
158
(Phenytoin/Fosphenytoin)
wptyjsustg(cfeglvrzqj) = fcjjcrrgwq ewqrbdycse (fiabsjqvwr, nvwxbonbiz - icoysyiyls)
-
05 Aug 2013
(Levetiracetam)
wptyjsustg(cfeglvrzqj) = njdfiquhgn ewqrbdycse (fiabsjqvwr, tlufbkyjhv - zkbgwnlolf)
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