Last update 15 Dec 2024

Olitigaltin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Bis-(3-deoxy-3-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-B-D-galactopyranosyl) sulfane, GB0 139, GB0-139
+ [1]
Mechanism
galectin-3 inhibitors(Galectin-3 inhibitors)
Inactive Indication
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (EU), Orphan Drug (US)
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Structure

Molecular FormulaC28H30F2N6O8S
InChIKeyYGIDGBAHDZEYMT-MQFIMZJJSA-N
CAS Registry1450824-22-2

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 2
GB
13 Jun 2020
Idiopathic Pulmonary FibrosisPhase 2
US
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
AU
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
BE
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
CA
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
FR
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
GE
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
DE
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
IE
19 Feb 2019
Idiopathic Pulmonary FibrosisPhase 2
IL
19 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
172
(A. GB0139 3 mg Once a Day)
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-
22 May 2024
Placebo
(B. Placebo Once a Day)
bhfrwifddu(eehfioevat) = ymamjszscg lveiqmvnii (npnduhtdad, udljaelxrm - vciascgfsu)
Not Applicable
-
-
TD139 Galectin-3 inhibitor
jpvbmngmix(myqycsklfj) = Release measurements under cell culture conditions showed release profiles ranging from one week to two months for the different modifications bxwikygpfa (nqdvdlvyvc )
-
19 May 2024
Phase 1/2
41
Standard of Care+GB0139
zyyjpovdiy(lkisssvbvk) = maxwewejpg wrzzmjbpji (xlaielsbsp )
Positive
22 Jun 2021
Standard of Care
-
Phase 1
60
sauazuksrd(xfuhblfdzg) = auxpqazxbj ljovxswddx (wpbbosofmt )
-
19 Nov 2020
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Approval

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Regulation

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