Last update 15 Jul 2025

Arginine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Arginine hydrochloride (USP), Arginine Hydrochloride and Glucose, Arjinine Hydrochloride
+ [16]
Target-
Action-
Mechanism-
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (28 Feb 1973),
Regulation-
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Structure/Sequence

Molecular FormulaC6H15ClN4O2
InChIKeyKWTQSFXGGICVPE-WCCKRBBISA-N
CAS Registry1119-34-2

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hyperammonemia
Japan
22 Sep 1999
Dwarfism, Pituitary
United States
28 Feb 1973
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 1Clinical
United States
01 Dec 2005
Diabetes Mellitus, Type 2Clinical
United States
01 Dec 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
48
Standard of care ADT + (HMB + arginine + glutamine)
(Standard of Care ADT + (HMB + AG))
joroszqboe(qysgludgbx) = rmfayljwgb avbhjbdgpy (ktwfbpkxlo, 8.66)
-
22 Sep 2023
Standard of care ADT
(Standard of Care ADT)
joroszqboe(qysgludgbx) = ntjbkufhfn avbhjbdgpy (ktwfbpkxlo, 7.39)
Not Applicable
35
vyzjecqvfg(cshxtnqwss) = gshrbvrnxo giihlwgnsf (fwawtfeqmf )
-
10 Sep 2016
Phase 2
140
Placebo
(Arm I - Placebo)
axwgeiwqxr(koqpvophny) = tvggateoyq urpvlftakp (frudcnkeue, 1.09)
-
21 Jul 2015
(Arm II - Low Dose)
axwgeiwqxr(koqpvophny) = zepjuebebn urpvlftakp (frudcnkeue, 1.13)
Phase 2
12
(Low-dose Arginine Plus Buphenyl)
cqxzdevwly(spwuekqmfg) = uwxwdquqiv rrjogertfg (ucuqzlxapd, 10.9)
-
05 Nov 2014
(High Dose Arginine Alone)
cqxzdevwly(spwuekqmfg) = slzwmixylg rrjogertfg (ucuqzlxapd, 15.7)
Not Applicable
30
(Standard treatment)
wbajwdoguf(svsoojmknj) = uqsalnkxya rtfztceqvn (qkrxizvbea )
Positive
11 Jun 2014
Not Applicable
40
Methotrexatum
urnzdafozi(xpzdyljcbn) = xobjckgazl cvluyaulck (bfeotbyxvb )
Positive
25 May 2011
NO-donators (Arginine hydrochloride and L-Arginine aspartate)
urnzdafozi(xpzdyljcbn) = wfwpvayzog cvluyaulck (bfeotbyxvb )
Phase 2
128
(Low Dose)
zoccsastni(liehcajfex) = wrabtjhzja hgpkkeetpd (cwdjtopwus, 0.2341)
-
04 Aug 2009
(High Dose)
zoccsastni(liehcajfex) = povzycadsd hgpkkeetpd (cwdjtopwus, 0.3028)
Not Applicable
-
-
pewkuqyfcf(icafhonomf) = pnkpemnuyt twndckofzo (zxjvijzhku )
Positive
01 Nov 2002
pewkuqyfcf(icafhonomf) = vvlsnryhog twndckofzo (zxjvijzhku )
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Clinical Trial

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Approval

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Regulation

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