Last update 09 Dec 2024

Etidronate Disodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(1-hydroxy-ethylidene)diphosphonic acid, (1-Hydroxyethylene)diphosphonic acid, (1-Hydroxyethylidene)bis(phosphonic acid)
+ [35]
Mechanism
Bone resorption factor inhibitors
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (EU), Orphan Drug (US)
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Structure

Molecular FormulaC2H8Na2O7P2
InChIKeyFCBYKAIUKRZZGW-UHFFFAOYSA-N
CAS Registry7414-83-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Ossification, Heterotopic
JP
28 Sep 1990
Osteoporosis
US
01 Sep 1977
Osteitis Deformans
US
01 Sep 1977
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Fahr's DiseasePhase 2
NL
03 Apr 2023
HEM DysplasiaPhase 2
NL
03 Apr 2023
ABCC6 deficiencyPreclinical
EU
11 Oct 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
7
MRI Scan+Etidronate
bisfxztzvx(qkfmnklxsz) = ostapqzfaz wbhwttlske (xmcsfkupnq, glabbkndum - cdzrapvcac)
-
04 Oct 2022
Not Applicable
Chronic glomerulonephritis | Glucocorticoid-induced osteoporosis
N-terminal telopeptide of type I collagen (NTx) | uncarboxylated osteocalcin (ucOC)
43
duqgfzlqog(hqillpizuu) = There were no significant differences in BMD between these groups during the study fhalvvgcvq (touszzoxut )
Positive
05 Nov 2013
Not Applicable
50
HRT
wzztepjups(vhupurtxlx) = tgkhidpyhw jyjvsfbnhu (ooqcebfuaw )
-
01 Feb 2009
Cyclical etidronate
wzztepjups(vhupurtxlx) = pwwgkxvxff jyjvsfbnhu (ooqcebfuaw )
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Approval

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Regulation

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