Drug Type Fusion protein |
Synonyms Ipafricept (USAN/INN), FZD8-FC, Fzd8-Fc + [2] |
Target |
Mechanism Wnt ligand inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 1 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Platinum-Sensitive Ovarian Carcinoma | Phase 1 | US | 01 Jan 2014 | |
Hepatocellular Carcinoma | Phase 1 | US | 01 Jan 2014 | |
Pancreatic Cancer | Phase 1 | US | 01 Nov 2013 | |
Solid tumor | Phase 1 | US | 01 Jun 2012 | |
Ovarian Cancer | Phase 1 | - | - |
Phase 1 | Pancreatic Cancer First line | 26 | znqneteldz(mabmemlrvd) = tvxcsllfzh xetwaifvbr (vslbxbakfn, 3.4 - 18.4) View more | Negative | 15 Oct 2020 | ||
Phase 1 | 37 | uozjhzgjfx(nancewhoyb) = dbxzosnxta qihsfftdjv (tvbaixsnho ) View more | Positive | 01 Aug 2019 | |||
Phase 1 | 26 | Ipafricept + Nab-P/G | wdritwfvwj(ibvcgcoqvo) = included 2 events of AST elevation, and 1 each of nausea, maculopapular rash, vomiting and WBC decrease eejigovaru (olfwfpimgb ) View more | Positive | 29 Jan 2019 | ||
NCT01608867 (Pubmed) Manual | Phase 1 | 26 | qgxngwgskc(levtexqzoe) = 15 mg/kg;Q3W jnylkzpamo (mwcztgaapn ) View more | Positive | 15 Dec 2017 | ||
Phase 1 | - | jjrulaxubx(rzorwdphrf) = induction kovbtwzcbj (njtahcgurs ) View more | Positive | 01 Oct 2014 | |||
Phase 1 | 25 | juzsxuzksd(hfomrnoood) = vsnacfxtwa rwprnfbgic (gpuwnuprbf ) View more | - | 20 May 2014 |