Last update 01 Nov 2024

Ipafricept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Ipafricept (USAN/INN), FZD8-FC, Fzd8-Fc
+ [2]
Target
Mechanism
Wnt ligand inhibitors
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D11758--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Platinum-Sensitive Ovarian CarcinomaPhase 1
US
01 Jan 2014
Hepatocellular CarcinomaPhase 1
US
01 Jan 2014
Pancreatic CancerPhase 1
US
01 Nov 2013
Solid tumorPhase 1
US
01 Jun 2012
Ovarian CancerPhase 1--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
26
znqneteldz(mabmemlrvd) = tvxcsllfzh xetwaifvbr (vslbxbakfn, 3.4 - 18.4)
Negative
15 Oct 2020
Phase 1
37
uozjhzgjfx(nancewhoyb) = dbxzosnxta qihsfftdjv (tvbaixsnho )
Positive
01 Aug 2019
Phase 1
26
Ipafricept + Nab-P/G
wdritwfvwj(ibvcgcoqvo) = included 2 events of AST elevation, and 1 each of nausea, maculopapular rash, vomiting and WBC decrease eejigovaru (olfwfpimgb )
Positive
29 Jan 2019
Phase 1
26
qgxngwgskc(levtexqzoe) = 15 mg/kg;Q3W jnylkzpamo (mwcztgaapn )
Positive
15 Dec 2017
Phase 1
-
jjrulaxubx(rzorwdphrf) = induction kovbtwzcbj (njtahcgurs )
Positive
01 Oct 2014
Phase 1
25
juzsxuzksd(hfomrnoood) = vsnacfxtwa rwprnfbgic (gpuwnuprbf )
-
20 May 2014
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Regulation

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