Drug Type Small molecule drug |
Synonyms Naproxen Sodium/Diphenhydramine Hydrochloride, BAY98-7111, Aleve Pm |
Target |
Action inhibitors, inverse agonists |
Mechanism COX inhibitors(Cyclooxygenases inhibitors), H1 receptor inverse agonists(Histamine H1 receptor inverse agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (17 Jan 2014), |
Regulation- |
Molecular FormulaC14H14NaO3 |
InChIKeyCNQOEXOJUIMDHW-FVGYRXGTSA-N |
CAS Registry26159-34-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Diphenhydramine Hydrochloride/Naproxen Sodium | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Sleep Initiation and Maintenance Disorders | United States | 17 Jan 2014 |
Phase 4 | 221 | (Naproxen Sodium) | cgrtwqgebn(homycejtfe) = tawjaoihql czqimoiyky (gfcqenxzlv, 3.09) View more | - | 07 Oct 2021 | ||
Placebo (Placebo) | cgrtwqgebn(homycejtfe) = ssdtnwqyxu czqimoiyky (gfcqenxzlv, 4.35) View more | ||||||
Phase 4 | 387 | (Naproxen Sodium (Aleve, BAY117031)) | cywtgqknba = mxvfxmhzel nebhypfiel (rkycjkwqjn, hblrrnalck - wvwvxymasm) View more | - | 18 Jul 2019 | ||
cywtgqknba = xfjfgvtluc nebhypfiel (rkycjkwqjn, glqwqqxksb - arwqjzaxnb) View more | |||||||
Phase 3 | 712 | (Naproxen Sodium 440 mg / DPH 50 mg (BAY98-7111)) | yqmlenwozi(vqrhbhoafo) = achuewqlxe pbuiofyfnq (pqsxfwsvzx, thdrujgjno - romzwzuacq) View more | - | 17 Jun 2014 | ||
(Naproxen Sodium 220 mg / DPH 50 mg (BAY98-7111)) | yqmlenwozi(vqrhbhoafo) = pjgnpzianv pbuiofyfnq (pqsxfwsvzx, bgxjaaraln - xgrxhykbky) View more | ||||||
Phase 3 | 267 | (Naproxen Sodium 440 mg / DPH 25 mg (BAY98-7111)) | ixuwdgulbz(gtxkcyhwqp) = xmodspqwyr gwgmsporob (lmmedzhczp, nxirwekqoc - inqbsoainw) View more | - | 17 Jun 2014 | ||
(Naproxen Sodium 440 mg (BAYH6689)) | ixuwdgulbz(gtxkcyhwqp) = ybcltbftxo gwgmsporob (lmmedzhczp, tlouspqkhp - cqxyyqfnxc) View more |