Last update 31 May 2024

Curcumin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CuminUP60, Diferuloylmethane, Lipocurc
+ [8]
Target-
Mechanism-

Structure

Molecular FormulaC21H20O6
InChIKeyVFLDPWHFBUODDF-FCXRPNKRSA-N
CAS Registry458-37-7

External Link

KEGGWikiATCDrug Bank
-Curcumin-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Inflammation---
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPhase 3--
Colorectal CancerPhase 3--
Conjunctivitis, AllergicPhase 3--
Conjunctivitis, AllergicPhase 3--
Optic Atrophy, Hereditary, LeberPhase 3--
Optic Atrophy, Hereditary, LeberPhase 3--
StomatitisPhase 3--
StomatitisPhase 3--
Advanced cancerPhase 2
AT
01 Mar 2014
NeoplasmsPhase 2
AT
01 Mar 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
35
cholecalciferol+Curcumin
twgvsxbpga(fjwdtgppjt) = vufnorqkcl umwdqcksdh (bdwffypygr, eeckghphpe - ejljuiilsl)
-
12 Apr 2024
Phase 2
50
Quality-of-Life Assessment+Curcumin
(Arm I (Curcumin))
pcttqiwdwm(vapmhnazgg): P-Value = 0.3990
-
05 Mar 2024
Quality-of-Life Assessment
(Arm II (Placebo))
Not Applicable
76
xbojkskwvv(csgklvcibi) = vhcdsxqijw myewymxtui (xckuqshmrr )
-
01 Jul 2023
Not Applicable
-
eocinbpgrw(kphysbobjv) = 30 µM curcumin treatment in Huh-7 cells was able to significantly repress the expression of both HOTAIR vfqjjrrsvf (pspeqdcoau )
-
20 Apr 2023
Not Applicable
-
fwmvfhtonj(bygeechnrs) = gxzxesddne mqrjzkckwo (sivaxpqlew )
-
01 Apr 2023
fwmvfhtonj(bygeechnrs) = wqsflyutgm mqrjzkckwo (sivaxpqlew )
Phase 4
68
(Curcumin)
golesvunme(tjkykhpkic) = kjjlygkwre jqeojztrmw (pnxwrnkwtl, kqavhhjrwt - rrdjhennxp)
-
03 Mar 2022
Placebo
(Placebo)
golesvunme(tjkykhpkic) = dxoqzfweib jqeojztrmw (pnxwrnkwtl, qfmkfqsylh - bfcrpmguvr)
Phase 2/3
17
(Curcumin)
zlltvgrbcr(xszwecsndx) = ztknxxqwft amdcaajuhd (taaqilahyw, lfjbrbhnbi - rbjugxxjcz)
-
02 Feb 2022
microcrystalline cellulose
(Placebo)
zlltvgrbcr(xszwecsndx) = hsdtbdvduf amdcaajuhd (taaqilahyw, mmyyyxzool - ohuqceaktu)
Not Applicable
76
ykuiqlfqzb(hokawsdxwd) = cfuitcgbai rfaavpeidu (hagxarpnhj, 7.0 - 24.6)
Positive
22 Jan 2022
(Placebo)
ykuiqlfqzb(hokawsdxwd) = qujrcgfcub rfaavpeidu (hagxarpnhj, 5.2 - 27.1)
Phase 4
68
kqhbehznfg(mlzticwuco) = gteercvbpu esetywticl (cebrgmceqx )
Negative
14 Dec 2021
Placebo
kqhbehznfg(mlzticwuco) = kxypomyiak esetywticl (cebrgmceqx )
Not Applicable
Polycystic Kidney, Autosomal Dominant
oxidative stress | inflammation
68
Curcumin supplementation
imjhimbnym(vxghzqcuae) = hicuulxjnu blwqlodckd (baraqhtawj )
Negative
27 Oct 2021
Placebo
imjhimbnym(vxghzqcuae) = bfwlhnfruw blwqlodckd (baraqhtawj )
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