Last update 23 Jun 2024

Muzastotug

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-CTLA-4 Monoclonal Antibody(Adagene), ADG-126, ADG126
Target
Mechanism
CTLA4 inhibitors(Cytotoxic T-Lymphocyte-Associated Antigen 4 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPhase 2
US
06 May 2024
Colorectal CancerPhase 2
CN
06 May 2024
Colorectal CancerPhase 2
HK
06 May 2024
Colorectal CancerPhase 2
KR
06 May 2024
Non-Small Cell Lung CancerPhase 2
US
06 May 2024
Non-Small Cell Lung CancerPhase 2
CN
06 May 2024
Non-Small Cell Lung CancerPhase 2
HK
06 May 2024
Non-Small Cell Lung CancerPhase 2
KR
06 May 2024
Solid tumorPhase 2
AU
15 Mar 2021
Solid tumorPhase 2
SG
15 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
47
fwvvbfxrgo(ktudocamvf) = qnnlcbfppi csksfarcot (fnkwuvvixk )
Positive
20 Jan 2024
(expansion cohort + ADG126 10 mpk Q6W)
nxgqfkzcsg(fsofikjzdp) = bxglfvjrrw cnnokvcbgu (xekdruqugl )
Phase 1/2
-
ewdtwyolfv(nprxjendca) = TRAEs ≥10% included diarrhea (17%), fatigue (17%), pruritus (13%), and rash (10%) in monotherapy. TRAEs (> 10%) included diarrhea (21%), fatigue (14%), pruritus (14%), rash (14%) and nausea (14%) in combination therapy. hobfczlqah (chdbbahtpe )
Positive
14 Apr 2023
Phase 1/2
11
tsjsqrwwyh(tlhwvydpdv) = Both ADG126 6 and 10 mg/kg dose levels on either Q3W or Q6W were well tolerated with no DLT. ciqjvkuxos (lhykhksozg )
Positive
14 Apr 2023
Phase 1
16
fpoxfhcynr(sbcqezcjjw) = gusibagaus goqxcehjpx (evsxbmbszc )
Positive
02 Jun 2022
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Regulation

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