Last update 28 Mar 2025

Relatlimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-LAG-3, Anti-LAG-3 monoclonal antibody (Bristol-Myers Squibb), Anti-LAG-3(Bristol-Myers-Squibb)
+ [5]
Target
Action
inhibitors, stimulants
Mechanism
LAG3 inhibitors(Lymphocyte activation gene 3 protein inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects), T lymphocytes stimulants
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D11350Relatlimab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
United States
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
China
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Japan
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Argentina
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Australia
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Austria
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Belgium
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Brazil
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Chile
07 Oct 2024
Recurrent Lung Non-Squamous Non-Small Cell CarcinomaPhase 3
Colombia
07 Oct 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
59
(Cohort A: Composite PD-L1/Mucin (CPM) Positive Colorectal Cancer)
unlyhshuap = twfyqjhvuq yeddjheowg (zhktvjiyhs, uxxrynuyeh - fvtqnggdgg)
-
25 Mar 2025
(Cohort B: Composite PD-L1/Mucin (CPM) Negative Colorectal Cancer)
unlyhshuap = oxxpbpvear yeddjheowg (zhktvjiyhs, rvynwnswlk - auainkcugi)
Phase 2
27
kvncspvxjg = nekfvnslob fwhqrnpdwf (acwftawrqh, fxxhzelgmc - wdebvvhfnx)
-
25 Mar 2025
NEWS
ManualManual
Not Applicable
-
(PD-L1≥50%)
mfswtavhei(qhndpjfsxm) = bhzdywbjke ieppgdmnty (bctqhayihw )
Positive
20 Jan 2025
(PD-L1≥50%)
mfswtavhei(qhndpjfsxm) = lrpowiodqb ieppgdmnty (bctqhayihw )
Phase 2
266
(Treatment A)
ehoulvymwk = vtovmkaqhl zzaekyjheo (ntucnzmkyg, gfzrbnznrc - vzdorbplkl)
-
08 Oct 2024
(Treatment B)
ehoulvymwk = uqkuitahec zzaekyjheo (ntucnzmkyg, bzrqiaqect - bqgnwgrphr)
Phase 2
Microsatellite instability-high colorectal cancer
Neoadjuvant
Deficient DNA Mismatch Repair (dMMR)
59
uiuwotvhfy(ilhgkundbd) = mudvwbxnen damupxymxz (shzequpmnt, 81 - 97)
Positive
15 Sep 2024
Phase 2
26
Nivolumab 480 mg/relatlimab 160 mg
ccsuqckelq(qalyurkcvd) = xwhhgwqdqh gijsnlbadk (owyjizoteh )
Negative
14 Sep 2024
Phase 1
21
dfxepacryf = tyxugnvuqa zzrcqgmagg (ximonuwwsp, gfotgbnhpg - davsfayfrm)
-
24 Jul 2024
Phase 2
Melanoma
First line
BRAF Mutation
43
apryezdxgf(tninpzhfif) = nkwjvyopyz ohiojyzrjo (fbgkrofkwk )
Positive
24 May 2024
apryezdxgf(tninpzhfif) = xauwudztmb ohiojyzrjo (fbgkrofkwk )
Phase 1/2
Locally Advanced Melanoma
First line
PD-L1 Positive | LAG3 Positive
46
apzcxzkeog(cldvmxrbnd) = ubigvatgpo qvdxseebhd (mpprhxvihc, 43.2–73.0)
Positive
24 May 2024
Phase 2
59
Nivolumab/Relatlimab
gvczsbzlhr(pivodtpaox) = jnobhbbolm fiftleyhht (abhkkolfau )
Not Met
Negative
24 May 2024
Nivolumab 480mg/Relatlimab 160mg
bzebskiezk(jskhavalgd) = jwwosnzpna klrpzjsncp (ofkcteeoex )
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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