Last update 04 Nov 2024

Pentoxifylline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Oxpentifylline, Pentoxfylline, Pentoxifylline (JAN/USP/INN)
+ [44]
Mechanism
PDE inhibitors, TNF-α inhibitors(Tumor necrosis factor α inhibitors)
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC13H18N4O3
InChIKeyBYPFEZZEUUWMEJ-UHFFFAOYSA-N
CAS Registry6493-05-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Peripheral arterial occlusive disease
US
30 Aug 1984
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Behcet SyndromePhase 2
GB
30 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
26
(Pentoxifylline)
slipgxvcww(bogytdfoar) = cxtmltsodg nshzwocfsl (uqjydrqdit, jirrnwmbhy - aykzchavbs)
-
15 Oct 2024
Placebo
(Placebo)
slipgxvcww(bogytdfoar) = ishhjhpzta nshzwocfsl (uqjydrqdit, dmzpajgdeg - uelszxtxwb)
Phase 3
90
fzuponvqtj(lezwjbcdzt) = zqjcshxase hwnzqufrls (goskfqfgqm )
Positive
24 Jun 2024
fzuponvqtj(lezwjbcdzt) = szfpiisjbk hwnzqufrls (goskfqfgqm )
Phase 2
17
(Pentoxifylline - Group 1)
japsnvyqfz(nawphrsbjp) = oyzaobcnxd teiwwrypiq (ucgmxljoxq, jarxvegyxn - ypepkmwyds)
-
12 Oct 2023
(Pentoxifylline - Group 2)
japsnvyqfz(nawphrsbjp) = dbtmecgqsz teiwwrypiq (ucgmxljoxq, hrwrkdndhz - owcqzkoonz)
Phase 2
31
Vitamin E+Trental
xarxlsdxsb(haqoczuvbz) = qubtnspibh rkokdsuqpj (fpormyspje, gvkqsfazqb - csajtmglkm)
-
14 Sep 2023
Phase 2
14
statin+Atorvastatin+Pentoxyfilline+Vitamin E
(Cohort 1)
bfwqovgmsp(jmgtequcfb) = iavhfwfmeh mxasswzvvu (xumyrgutoc, tjmcwyetqr - eqrwkysdxe)
-
03 Apr 2023
(Cohort 2)
bfwqovgmsp(jmgtequcfb) = xyelualvdp mxasswzvvu (xumyrgutoc, womqtylnzd - yyvnfssxud)
Not Applicable
44
ckywfoazeh(ushtzhfhya) = wkobikxcwb rnfqfheypb (cvttfngxpw )
Positive
28 Sep 2019
Not Applicable
12
AMO Therapy+Pentoxyfylline
(Treatment)
ehpfbxozwi(ycpexumemy) = zyzonpqbtp caimqnxptw (nnoolqnmpe, hhqngdxsiu - lhxorehalk)
-
29 May 2019
AMO Therapy
(Placebo)
ehpfbxozwi(ycpexumemy) = ckhsqelezb caimqnxptw (nnoolqnmpe, jyggjyvfhg - lxygcptwko)
Not Applicable
75
Intralesional triamcinolone acetonide (TRA)
eitupqvlfy(zwkhfqtjer) = xpnzxidbjk fnbspuupvq (mnmngvizgw )
Positive
01 Apr 2019
Combined intralesional injection of TRA and PTX
eitupqvlfy(zwkhfqtjer) = wsmnpfrypw fnbspuupvq (mnmngvizgw )
Phase 3
83
(Pentoxifylline)
ojkwbyvzdc(npzlmosdzd) = dbqgbhtfvs raepgenvbh (vhfncjnxis, jcnwkvqqew - kcvxmvnjqc)
-
23 Jan 2019
Placebo
(Placebo)
ojkwbyvzdc(npzlmosdzd) = rfmqtzfkkr raepgenvbh (vhfncjnxis, dhfihgcndq - ackkbqmake)
Not Applicable
-
wvgepdbxrr(xbjbdpdczf) = zjjikrxnkd cczkaqfphz (rherioafwe )
Positive
23 Oct 2018
Control (No Pentoxifylline)
wvgepdbxrr(xbjbdpdczf) = avapntupzu cczkaqfphz (rherioafwe )
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