Last update 01 Nov 2024

JI-101

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mechanism
EphB4 antagonists(Ephrin type-B receptor 4 antagonists), PDGFRβ inhibitors(Platelet-derived growth factor receptor beta inhibitors), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists)
Active Indication
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urologic NeoplasmsPhase 1
US
20 May 2011
Urologic NeoplasmsPhase 1
IN
20 May 2011
Urologic NeoplasmsPhase 1
US
20 May 2011
Colonic CancerDiscovery
US
01 Sep 2010
Ovarian CancerDiscovery
US
01 Sep 2010
RAS mutant Colorectal CancerDiscovery
US
01 Sep 2010
Advanced Malignant Solid NeoplasmDiscovery
US
01 Feb 2009
NeoplasmsDiscovery--
NeoplasmsDiscovery--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
19
(Pharmacokinetic Arm)
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-
25 Sep 2014
(Pharmacodynamic Arm)
thpupnlmnz(fijlcilaoe) = ofcmblhgal bhaoojhddi (nffsncbyjl, qrkptqrfis - jtoipomvtq)
Phase 1/2
18
voqvryjxkt(yhtkwhadzn) = oeezxgxplb aypmmqhubk (zpynkmqlve, xtnxelvdpf - ovylfpczvt)
-
24 Jun 2013
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Regulation

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