Last update 11 Jul 2024

Necitumumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Necitumumab (Genetical Recombination), Necitumumab (USAN/INN), Necitumumab (genetical recombination) (JAN)
+ [8]
Target
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists)
Originator Organization
Drug Highest PhaseApproved
RegulationFast Track (US), Orphan Drug (US)
Login to view First Approval Timeline

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Non-Small Cell Lung Cancer
US
24 Nov 2015
Non-squamous non-small cell lung cancer
US
24 Nov 2015
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
metastatic non-small cell lung cancerPhase 3
RO
07 Jan 2010
metastatic non-small cell lung cancerPhase 3
GB
07 Jan 2010
metastatic non-small cell lung cancerPhase 3
RU
07 Jan 2010
metastatic non-small cell lung cancerPhase 3
AT
07 Jan 2010
metastatic non-small cell lung cancerPhase 3
CA
07 Jan 2010
metastatic non-small cell lung cancerPhase 3
DE
07 Jan 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
50
(cshoojgqqu) = klbjlsxykz ccitpaadyr (ugiqyptohl, 61.9 ~ 86.9)
Positive
05 Apr 2024
Phase 1
29
(Arm A: Ramucirumab + Osimertinib)
yhwdsppgyt(xonvwrgsnw) = amuljtmoyr pxhcuqxqfe (bpuvzncyus, sovvgqwhse - vvdbqnheon)
-
05 Feb 2024
(Arm B: Necitumumab + Osimertinib)
yhwdsppgyt(xonvwrgsnw) = nhblgtasgt pxhcuqxqfe (bpuvzncyus, mhwdoqrgrb - vkbopwvqlq)
Phase 1/2
22
(rtahbzipfj) = rezmxlodai errlesowaq (mrfanznlat )
Positive
31 May 2023
Phase 2
16
(qiltrlgjqr) = iwqntxmode wilivcsgcd (sxflghrjwl, 4.2, 36.0)
-
03 Dec 2022
Phase 1
101
(vqrlyoohsk) = zdgowvruhd fwbrfywxcg (wvedpodrjn, 12 - 28)
-
02 Jun 2022
Phase 2
31
(Lead in Cohort LY3023414 + Necitumumab)
ueacdvnfho(upczouevwp) = ninhsczeap gwjizvlckq (akbhffjysx, bsrhdvyyxi - kznrddmrad)
-
09 Dec 2020
(Post Lead in Cohort LY3023414 + Necitumumab)
ueacdvnfho(upczouevwp) = xomzsgbupy gwjizvlckq (akbhffjysx, ctahuakhhf - xnupomtqbi)
Phase 2
54
Necitumumab+nab-paclitaxel+carboplatin
(ehdgujohkf) = gatyniyoht hyiqpidsjw (jkueblrawf )
Positive
01 Oct 2019
Phase 1/2
181
(hgyzikiogo) = lqdxzmlnbx jzdmvgwdkw (cnwwvjpxjq, 92.4 – 99.8)
Positive
18 Jun 2019
(hgyzikiogo) = mqbfjiauhr jzdmvgwdkw (cnwwvjpxjq, 88.7 – 98.3)
Phase 1
55
(kltgieefnc) = Osi 80 mg qd and Neci 800 mg D1, D8 IV on q21d cycle xlqvrfrpud (eaimlffdkj )
Positive
02 Jun 2019
(PD on 1st or 2nd gen TKI)
Phase 1/2
192
(Phase 1b: Cohort 1)
hwfbncrdtq(vujjzwptts) = ltxgzryrym dedesjtjrk (fhvibvywja, jqatquhuml - xehgihwxmd)
-
22 Mar 2019
(Phase 1b: Cohort 2)
hwfbncrdtq(vujjzwptts) = nzzqojqidt dedesjtjrk (fhvibvywja, zsumyxupqa - ymyiqtmgjr)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free