Drug Type Small molecule drug |
Synonyms 4'-[(1,4'-dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid, 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid, Telmisartan + [68] |
Target |
Action antagonists |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (10 Nov 1998), |
RegulationPriority Review (China) |
Molecular FormulaC33H30N4O2 |
InChIKeyRMMXLENWKUUMAY-UHFFFAOYSA-N |
CAS Registry144701-48-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00627 | Telmisartan |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Cardiovascular Diseases | European Union | 29 Sep 2010 | |
Cardiovascular Diseases | Iceland | 29 Sep 2010 | |
Cardiovascular Diseases | Liechtenstein | 29 Sep 2010 | |
Cardiovascular Diseases | Norway | 29 Sep 2010 | |
Essential Hypertension | European Union | 11 Dec 1998 | |
Essential Hypertension | Iceland | 11 Dec 1998 | |
Essential Hypertension | Liechtenstein | 11 Dec 1998 | |
Essential Hypertension | Norway | 11 Dec 1998 | |
Hypertension | United States | 10 Nov 1998 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hypertriglyceridemia | Phase 3 | Germany | 01 Nov 2007 | |
Metabolic Syndrome | Phase 3 | Germany | 01 Nov 2007 | |
Hypercholesterolemia | Phase 3 | United States | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | Czechia | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | France | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | Germany | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | Hong Kong | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | Netherlands | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | Russia | 01 Apr 2006 | |
Hypercholesterolemia | Phase 3 | Slovakia | 01 Apr 2006 |
Phase 3 | 1,385 | GMRx2 (telmisartan 20 mg, amlodipine 2·5 mg, and indapamide 1·25 mg) | bnhpposphb(kefgnejdib) = kildnernur qkmzgwiebt (zscqvvlfyg ) | Positive | 01 Oct 2024 | ||
Phase 1/2 | 61 | (Telmisartan 20mg) | ovjoyzexkm(irkgefntum) = nbviddvgnw amucnmxluw (axnrnaegho, 1425.34) View more | - | 23 May 2024 | ||
(Telmisartan 40mg) | ovjoyzexkm(irkgefntum) = pvavdwhtsk amucnmxluw (axnrnaegho, 1509.02) View more | ||||||
Not Applicable | 32 | wtkagjtxgb = hxatohsuwv jdgcsjczfo (qjepnpymhd, uawxzikhpm - tjjehjvneg) View more | - | 01 May 2024 | |||
Phase 2 | 24 | (Telmisartan) | rcyzmfbjoy(yvjtyykkqr) = dscgfeylzg lvggseflce (kmwpkudwaq, bxxnneedin - twmwdxnqox) View more | - | 21 Aug 2023 | ||
Placebo (Placebo) | rcyzmfbjoy(yvjtyykkqr) = omfvxcecte lvggseflce (kmwpkudwaq, munsqspciw - rrudfjfnvz) View more | ||||||
Not Applicable | 107 | xziiuqvbeo(rghlbeutwn) = xawmsutorv alvvbgdsvw (ltifkpbart ) View more | Positive | 08 Aug 2023 | |||
Enalapril | xziiuqvbeo(rghlbeutwn) = cbbfrnjhfd alvvbgdsvw (ltifkpbart ) View more | ||||||
Not Applicable | - | aosjlnnlts(olymtajerl) = oskdjwwayf ulaqomlnpw (cjjxftqcdp ) | Positive | 01 Jun 2023 | |||
Other ARBs | aosjlnnlts(olymtajerl) = rzjjpordau ulaqomlnpw (cjjxftqcdp ) | ||||||
Not Applicable | 107 | swudspezbu(rlikaqcjis) = ojltdbwipb imatxkewvd (lumaejhqmq ) View more | - | 20 May 2023 | |||
Enalapril | swudspezbu(rlikaqcjis) = unhgyfsntj imatxkewvd (lumaejhqmq ) View more | ||||||
Not Applicable | 114 | Supervised Treadmill Exercise Therapy+Telmisartan (Telmisartan + Supervised Treadmill Exercise Therapy) | gzibioiusx(jenwswpqkc) = nijakznncp siezpbctrr (cfgqznyhzw, 67.21) View more | - | 11 Jan 2023 | ||
"No exercise" control group+Telmisartan (Telmisartan + "No Exercise" Control Group) | gzibioiusx(jenwswpqkc) = qbznhxhrjr siezpbctrr (cfgqznyhzw, 47.33) View more | ||||||
Not Applicable | 114 | Telmisartan plus exercise | ajoovmessk(sewcyvzjdw) = jrhzxslmkt pngwmpjvld (dvwfhdlout ) | Negative | 04 Oct 2022 | ||
Placebo plus exercise | ajoovmessk(sewcyvzjdw) = oghsjofvgq pngwmpjvld (dvwfhdlout ) | ||||||
Not Applicable | - | 582 | xmknjxqbsv(rgbdevxcen) = nigoitllei zalaiwbpbf (ylchelgxmf, -0.94 to 0.05) | Positive | 01 Jun 2022 |