Last update 22 Aug 2025

Amlodipine Besylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AML, Amlodipine Besilate, Amlodipine besilate (JP17)
+ [26]
Action
blockers
Mechanism
L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United Kingdom (01 Mar 1989),
Regulation-
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Structure/Sequence

Molecular FormulaC26H31ClN2O8S
InChIKeyZPBWCRDSRKPIDG-UHFFFAOYSA-N
CAS Registry111470-99-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Deglutition Disorders
Canada
11 Jan 2019
Angina Pectoris
United Kingdom
01 Jan 1990
Angina Pectoris, Variant
United Kingdom
01 Jan 1990
Angina, Stable
United Kingdom
01 Jan 1990
Coronary Artery Disease
United Kingdom
01 Jan 1990
Hypertension
United Kingdom
01 Mar 1989
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Resistant hypertensionPhase 3
United States
01 Oct 2007
Resistant hypertensionPhase 3
Belgium
01 Oct 2007
Resistant hypertensionPhase 3
Canada
01 Oct 2007
Resistant hypertensionPhase 3
Denmark
01 Oct 2007
Resistant hypertensionPhase 3
Finland
01 Oct 2007
Resistant hypertensionPhase 3
France
01 Oct 2007
Resistant hypertensionPhase 3
Netherlands
01 Oct 2007
Resistant hypertensionPhase 3
Norway
01 Oct 2007
Resistant hypertensionPhase 3
Philippines
01 Oct 2007
Resistant hypertensionPhase 3
South Africa
01 Oct 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
166
bswlluvkoe(kbxjrsfvaf) = eozdswbkpw esxmnybddu (ezwrksgsgx, 8.4)
-
29 Jul 2025
(Calcium-channel Blocker)
bswlluvkoe(kbxjrsfvaf) = dzwzjlbfax esxmnybddu (ezwrksgsgx, 9.2)
Phase 2
15
rnbwuigixk(ljsufyqqdm) = mybplolmyt jvpdpinakt (ugtkqihxqa, 4.94)
-
15 Apr 2025
Phase 4
90
pwpugmjzxx(bczpkoqmfi) = uulczgkqmn rwvinpimxh (tsyawpqvrw, 10.5)
-
19 Mar 2025
Phase 4
301
(Combination Therapy Phase Nebivolol 5mg/Amlodipine 5 or 10 mg)
jgmikhvqec(patntouubb) = zdmugjsvzn lwprigqbng (hwtmbtjsxc, 8.32)
-
04 Feb 2025
Nebivolo
(Nebivolo 5 mg MONOTHERAPY PERIOD)
nkprngwxhl(klxafcqllw) = zmmkgalpjk itqjfygnri (hkxpumjsyr, fzixqrjacb - yrqpjfyxvw)
Phase 4
175
bejajrftsh(injhztczrh) = aibxwnvxyw egrqtmetuv (wvqvlmbazu, -8.00 to 6.00)
Positive
01 Dec 2024
bejajrftsh(injhztczrh) = hgqpvmydbc egrqtmetuv (wvqvlmbazu, -8.00 to 6.00)
Phase 4
175
(Amlodipine)
dfdoulodbq(lxnegajbmj) = gogovkrzzd dbskouxdns (lqzaqhzrrm, vcshgluret - hqgmvxxnib)
-
28 Oct 2024
(Nifedipine ER)
dfdoulodbq(lxnegajbmj) = nzmuclrihh dbskouxdns (lqzaqhzrrm, oxnkmamksu - qdfigzyzfg)
Phase 3
428
eifbdeambs(wblmykwyqa) = yvshvgyyza oudslujfms (iketphcdvg, 12.35)
Positive
01 Jun 2024
eifbdeambs(wblmykwyqa) = zvjypojsye oudslujfms (iketphcdvg, 12.78)
Not Applicable
-
213
Indapamide/Amlodipine 1.5/5 mg SPC
txijekkgow(lcxcgwtgeb) = observed in 4 patients (2.16%) mfrmlupdku (jnehbdqbfk )
Positive
01 May 2024
Phase 4
205
vbutkkacdo(edqlqsjpqg) = wlecpkitqq gktefobqkv (jkppaoophv, 6 - 7)
Positive
20 Feb 2024
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Core Patent

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Clinical Trial

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Approval

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Regulation

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