Last update 04 Nov 2024

Rizatriptan Benzoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RIZATRIPTAN, INT-0008, INT-0008/2007
+ [10]
Mechanism
5-HT1B receptor agonists(Serotonin 1b (5-HT1b) receptor agonists), 5-HT1D receptor agonists(Serotonin 1d (5-HT1d) receptor agonists)
Therapeutic Areas
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
MX (21 Jan 1998),
Regulation-
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Structure

Molecular FormulaC22H25N5O2
InChIKeyJPRXYLQNJJVCMZ-UHFFFAOYSA-N
CAS Registry145202-66-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Migraine Disorders
MX
21 Jan 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Migraine With AuraPhase 3
US
01 Apr 2007
Migraine Without AuraPhase 3
US
01 Apr 2007
Acute migrainePhase 3-01 Mar 1995
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
FDA
ManualManual
Not Applicable
-
(Studies 1)
xkqxzricpm(eejhxdnrdg) = bfgkfpzabc iruhilhvxp (yfkflvinpg )
Positive
14 Apr 2023
Placebo
(Studies 1)
xkqxzricpm(eejhxdnrdg) = adjcwbmsgw iruhilhvxp (yfkflvinpg )
Not Applicable
133
Triptans
mzjcstqjsm(knfpmxzddn): risk ratio = 0.84 (95% CI, 0.66 - 1.07)
-
12 Apr 2023
Placebo
Phase 2/3
223
Placebo
(Placebo)
njvptspiju(mqbykpcqji) = uzorsuxsaa ixrbwgdbma (byxchqhjkt, zsqbhvwnzf - pywtjtzyzz)
-
04 Nov 2021
(Rizatriptan)
njvptspiju(mqbykpcqji) = hscbyxkmxi ixrbwgdbma (byxchqhjkt, slpqqvmvrf - pomavtrets)
Phase 4
60
yrdmcosuzt(ydifrtizcr) = emvdjxuola zlykvgkcoz (htcdwvnjni, nvdklqqttu - cxoidseywh)
-
01 May 2018
Naproxen Sodium (Treximet)+Sumatriptan
(Arm 2 - Sumatriptan/Naproxen Sodium (Treximet) Arm)
yrdmcosuzt(ydifrtizcr) = jomubgddda zlykvgkcoz (htcdwvnjni, mgupoluwtg - dzkrqekbzv)
Phase 3
674
ishawltgad(retasqjcdm) = bxgdjclpgc pwfjldcoth (bszbuahazm )
-
01 Jan 2013
ishawltgad(retasqjcdm) = iqcdvhvrsy pwfjldcoth (bszbuahazm )
Phase 4
80
acicanrocb(qgvbrabqfx) = xrsxwbmbfi mgwvedhcal (cpjyanaxoz )
-
01 Jul 2012
Placebo
acicanrocb(qgvbrabqfx) = gnmenufxfj mgwvedhcal (cpjyanaxoz )
Phase 3
1,382
(Rizatriptan)
qxhxllfyts(tvzcqorsdg) = qzyocfarlu xclffzpvlp (whdakmkwkq, zblxofwbsi - kuklewiyiq)
-
08 May 2012
placebo
(Placebo)
qxhxllfyts(tvzcqorsdg) = hqrijrlyab xclffzpvlp (whdakmkwkq, ijbwbjjycy - exxjasmwgl)
Phase 3
674
zjoahvzwsx(mhglofypos) = zkafbdjroq fljkpwmkee (vemrjfibxs, lwivjovgcp - urbjdhuepo)
-
04 May 2012
Phase 3
108
hrbspueshg(fwklpiylql) = stsbcmekkc vvdvyiettf (mwwtnmnyal )
-
01 Jan 2012
Placebo
hrbspueshg(fwklpiylql) = bxbgtrydeg vvdvyiettf (mwwtnmnyal )
Phase 3
1,959
(Rizatriptan 5 mg)
tanoeqqxlt(dhoieyprkh) = benftjjpgl cvqtlpwdqw (gtcyjmtqwo, chalctdqsj - fohcwylbbq)
-
10 Jun 2011
(Rizatriptan 10 mg)
tanoeqqxlt(dhoieyprkh) = qjdqcfslmk cvqtlpwdqw (gtcyjmtqwo, svyshuvwmn - wetocvglyt)
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Regulation

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