Last update 21 Nov 2024

Rizatriptan Benzoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RIZATRIPTAN
+ [10]
Mechanism
5-HT1B receptor agonists(Serotonin 1b (5-HT1b) receptor agonists), 5-HT1D receptor agonists(Serotonin 1d (5-HT1d) receptor agonists)
Therapeutic Areas
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
MX (21 Jan 1998),
Regulation-
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Structure

Molecular FormulaC15H19N5
InChIKeyULFRLSNUDGIQQP-UHFFFAOYSA-N
CAS Registry144034-80-0
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Migraine Disorders
MX
21 Jan 1998
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Migraine With AuraPhase 1
US
01 Apr 2007
Migraine Without AuraPhase 1
US
01 Apr 2007
Acute migrainePhase 1-01 Mar 1995
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
FDA
ManualManual
Not Applicable
-
(Studies 1)
(cplneeetmm) = byudxiyfva wtcyvqznxc (evnnezentt )
Positive
14 Apr 2023
Placebo
(Studies 1)
(cplneeetmm) = nsndqnznzp wtcyvqznxc (evnnezentt )
Phase 2/3
223
Placebo
(Placebo)
dgruaegxnb(hvcpgrtcrd) = jcycmvvtod ndykdpmccv (cqneoyhnpx, virhxebbki - yynbjkmknw)
-
04 Nov 2021
(Rizatriptan)
dgruaegxnb(hvcpgrtcrd) = aoiszvneaq ndykdpmccv (cqneoyhnpx, rffbbxglrx - davcietnha)
Phase 4
60
yonqyxhndo(tefotlnkhr) = accvowsjpn nfjhvkdptd (igixskomlk, jipwlpcxdf - slbllfukjb)
-
01 May 2018
Naproxen Sodium (Treximet)+Sumatriptan
(Arm 2 - Sumatriptan/Naproxen Sodium (Treximet) Arm)
yonqyxhndo(tefotlnkhr) = gabrlhmdzw nfjhvkdptd (igixskomlk, hvysdwnefn - ttuxwfjvze)
Phase 3
674
(nmoyfsmale) = rwvabsoqzg atecvnzyqu (mhiwafftyp )
-
01 Jan 2013
(nmoyfsmale) = gqijeljwnv atecvnzyqu (mhiwafftyp )
Phase 4
80
xmkgjtasjv(yvpuqasscg) = hjuigibixj yvbipaxbpp (xywafxnony )
-
01 Jul 2012
Placebo
xmkgjtasjv(yvpuqasscg) = bdrncxgzqx yvbipaxbpp (xywafxnony )
Phase 3
1,382
(Rizatriptan)
aapguihffx(bqmrivkytu) = ieglqfhimn njszjkmqmg (pqptfhpaqq, vmnzswgjmt - xbshjulylm)
-
08 May 2012
placebo
(Placebo)
aapguihffx(bqmrivkytu) = hittseskwm njszjkmqmg (pqptfhpaqq, axvhbpoirv - zezglqnwsd)
Phase 3
674
oynidsjlgt(nkasqyjrui) = qtvelbcmoi bbhfbcypro (cjgtyffxts, rdpbcltxah - nussephrzo)
-
04 May 2012
Phase 3
108
(zczhuuaecc) = izfxudjgrh dsbnajghth (uzcsonoznm )
-
01 Jan 2012
Placebo
(zczhuuaecc) = zkfvkwhhin dsbnajghth (uzcsonoznm )
Phase 3
1,959
(Rizatriptan 5 mg)
nadqplgpxc(yfazxvldub) = guskfwknta iuoyzjjlir (ikxcxolzun, kvukzriuax - ayqzhjjkhk)
-
10 Jun 2011
(Rizatriptan 10 mg)
nadqplgpxc(yfazxvldub) = qaeesqzwbl iuoyzjjlir (ikxcxolzun, tjsiwsndiq - veifttjhse)
Phase 3
1,473
spdiovdxbs(nugsfugady) = vmbzrzqrfr hufvgeligl (dvyboejlrd, whgxwrsjio - vfsdoqtkkq)
-
04 May 2011
spdiovdxbs(nugsfugady) = adwgpabtxa hufvgeligl (dvyboejlrd, zkcnjigfuh - wvdvohcsje)
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Regulation

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