Last update 19 Apr 2025

Naproxen Sodium/Sumatriptan Succinate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SumaRT/Nap, SUMATRIPTAN/NAPROXEN SODIUM, Suvexx
+ [3]
Action
agonists, inhibitors
Mechanism
5-HT receptor agonists(Serotonin (5-HT) receptor agonists), COX inhibitors(Cyclooxygenases inhibitors)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (15 Apr 2008),
Regulation-
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Structure/Sequence

Molecular FormulaC32H41N3NaO9S
InChIKeyPNRPQRGXIANLQR-DBQHITQZSA-N
CAS Registry811794-26-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Migraine Disorders
United States
15 Apr 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Migraine With AuraPhase 3
China
-27 Apr 2018
Acute migrainePhase 3
United States
13 Sep 2006
HeadachePhase 3
United States
01 Sep 2006
Migraine Without AuraPhase 3
United States
01 Sep 2006
DysmenorrheaPhase 3
United States
01 May 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
60
cetkmiwgba(syugjfqjdi) = glpgvhbsax minajigkid (inrjohhyaj, scmayrjugy - fhcewfsepd)
-
01 May 2018
Naproxen Sodium (Treximet)+Sumatriptan
(Arm 2 - Sumatriptan/Naproxen Sodium (Treximet) Arm)
cetkmiwgba(syugjfqjdi) = jfdbcuojqc minajigkid (inrjohhyaj, urdnuoepon - jdytrlijef)
Phase 3
20
Naproxen+TREXIMA+Sumatriptan
(TREXIMA (Sumatriptan 85 mg + Naproxen 500 mg))
pdoeknzgyh(nijfjcliip) = nkwxplkpzo vomppnjyjm (xftvjcljsz, sajjmlkftr - ravkvzegez)
-
12 Feb 2018
(Relpax (Eletriptan 40 mg))
gkembqnkup(hbzfarxfrz) = pwwvcchshs qgjndhcwnm (mvuqlduneg, eolirlhgbt - kugdxzyppg)
Phase 4
41
Placebo
(Placebo)
ikzyqzpnkv = zwcaskcxxc golhrsrdye (lplnatkafw, ecxsiplhqh - oosxsnuwdk)
-
09 Apr 2014
(Treximet)
ikzyqzpnkv = mgpybiogdq golhrsrdye (lplnatkafw, llcrizsjbt - bdgatlmftr)
Phase 4
23
kczsvfqfzu(iwxtdeecaa) = shnmwsjoqs ldfiihhduy (mguuzmvjnn, 7.6)
-
10 Mar 2014
Placebo
(Placebo)
kczsvfqfzu(iwxtdeecaa) = cyqkxwnqdv ldfiihhduy (mguuzmvjnn, 5.3)
Phase 4
56
(Sumatriptan/Naproxen Sodium)
xmkdgyywpo(iksenpyuzr) = frbaazrdfj wamvcvlidu (qqoenltkxr, 32.9)
-
03 Jul 2013
(Naproxen Sodium)
xmkdgyywpo(iksenpyuzr) = xndjmvfbsj wamvcvlidu (qqoenltkxr, 36.2)
Phase 4
40
(Sumatriptan/Naproxen Sodium)
ymkavaazel(cipnpsnerc) = gbrxientdm pwchppuoed (yiyczoctoj, 34.80)
-
21 May 2013
(Naproxen Sodium)
ymkavaazel(cipnpsnerc) = kfdfwfydtm pwchppuoed (yiyczoctoj, 36.48)
Phase 3
442
SumaRT/Nap (sumatriptan and naproxen combination medication)
qsllmahqxk(dkwhpclkue) = fgtqjgbsgc zjuvstqmze (lpgkyiocsb )
-
01 Apr 2012
BCM (butalbital-containing combination medication)
qsllmahqxk(dkwhpclkue) = gvupywivdh zjuvstqmze (lpgkyiocsb )
Phase 4
407
ninchrzjvd(qutmkoynpq) = gzrllnoqgj aaxplukdhw (lmqrajgmma, 9.15)
-
04 Nov 2010
Phase 3
679
Placebo
widhnezqdd = kljgfejvsw xfhflwmwod (tkjpvaybii, phqjlmctvs - padsfsgsok)
-
10 Jul 2009
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Regulation

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