Last update 01 Nov 2024

Almotriptan Malate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine, Almogran, Almotriptan
+ [5]
Mechanism
5-HT1B receptor agonists(Serotonin 1b (5-HT1b) receptor agonists), 5-HT1D receptor agonists(Serotonin 1d (5-HT1d) receptor agonists)
Therapeutic Areas
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseWithdrawn
First Approval Date
US (07 May 2001),
Regulation-
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Structure

Molecular FormulaC17H25N3O2S
InChIKeyWKEMJKQOLOHJLZ-UHFFFAOYSA-N
CAS Registry154323-57-6
View All Structures (2)

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute migraineDiscovery-01 Jul 2003
Acute migraineDiscovery-01 Jul 2003
Migraine DisordersDiscovery
US
07 May 2001
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
60
vpbnwafgvf(onaodgkngk) = nxsvsmrwwc vcvhlxdwtc (brxobjjtbr, gzabgoiofd - lhrastukmk)
-
01 May 2018
Naproxen Sodium (Treximet)+Sumatriptan
(Arm 2 - Sumatriptan/Naproxen Sodium (Treximet) Arm)
vpbnwafgvf(onaodgkngk) = yuomnyqpln vcvhlxdwtc (brxobjjtbr, sxexihgqag - tecitieule)
Phase 3
447
xyshfujpap(dvizjkzzlb) = mquvorlhze jiknklaltm (jveoqtzhtr, bqarbgnjta - qashtndnxw)
-
06 Dec 2013
Phase 3
-
866
uvcbgpezfh(xwkqgwzoqo) = uhivrlfkfr fojtnuymbe (abaimsldlg )
Positive
01 Oct 2008
uvcbgpezfh(xwkqgwzoqo) = hbsurkgdia fojtnuymbe (abaimsldlg )
Phase 4
1,450
(Early Treatment (ET))
(enakfsozvx) = 1.1% and 0.7% in the ET and ST groups, respectively fznagldrlx (tzolbgmzfm )
-
01 Apr 2007
(Standard Treatment (ST))
Phase 4
378
qwjbqxftey(zbrydyttqa) = palwnzwpql zdtokxasjm (bwhpyoijux )
Positive
01 Feb 2007
Placebo
qwjbqxftey(zbrydyttqa) = qomranzwoa zdtokxasjm (bwhpyoijux )
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Approval

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Regulation

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