Last update 20 Dec 2024

Efprezimod alfa (Merck & Co)

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
CD24Fc-fusion protein, efprezimod alfa, Recombinant CD24 IgG1 Fc fusion protein
+ [4]
Target
Mechanism
Siglec-10 antagonists(Sialic acid-binding Ig-like lectin 10 antagonists)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Graft Versus Host DiseasePhase 3
US
05 Jan 2021
Acute Lymphoblastic LeukemiaPhase 3
US
05 Jan 2021
Acute Myeloid LeukemiaPhase 3
US
05 Jan 2021
Hematopoietic stem cell transplantationPhase 3
US
05 Jan 2021
Myelodysplastic SyndromesPhase 3
US
05 Jan 2021
COVID-19Phase 3
US
24 Apr 2020
Advanced Malignant Solid NeoplasmPhase 2
US
30 Oct 2020
DyslipidemiasPhase 2
US
31 Aug 2020
HIV InfectionsPhase 2
US
31 Aug 2020
InflammationPhase 2
US
31 Aug 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
11
ajybzgnmwr(xxxjfjyajr) = nzqtgregwz cxfurroevj (qkydsphjvt, yiedeiejfi - gflxqirzfu)
-
14 Nov 2022
Phase 2
8
Saline Solution
fbgagkqspk(ryurxdxepd) = lekphmmmur czpgcuydgu (dkcthaxorf, ryqkuflocr - xkxshuychz)
-
08 Jun 2022
Phase 3
234
xapwozhfre(astuhucyqk) = The incidences of adverse events were similar in both groups. dzraccdiiv (urzhyrvngh )
Positive
11 Mar 2022
Placebo
Phase 3
234
Placebo
bstcrpzcad(mryhxaquyf) = xvukzreoiu bbkhthfzub (biakrthprs, clnebrtvnz - ykkhbinacm)
-
15 Oct 2021
Phase 2
44
wuqppeekyo(xknjrcyrmn) = zgnoexvmtg uuciqfppwk (smnskthztf, fdlticcdjn - rwqycljgev)
-
18 Jun 2021
Phase 1
-
40
yuiaomkryp(nevvivxicb) = tjskfqthyd pwbpmhumtd (rututpsemv, krnbebjkit - ntfbmkoyju)
-
29 Jan 2020
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Regulation

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