Last update 01 Nov 2024

ARC-100

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [1]
Target
Mechanism
Tubulin inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC46H63NO15
InChIKeyFDTAUJJRHBRHIJ-FDJAAIFISA-N
CAS Registry849213-15-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPhase 2--
MedulloblastomaPhase 2--
MedulloblastomaPhase 2--
NeuroblastomaPhase 2--
NeuroblastomaPhase 2--
Glioblastoma MultiformePreclinical
US
01 Apr 2010
Pancreatic carcinoma non-resectablePreclinical
US
01 Oct 2007
Pancreatic carcinoma non-resectablePreclinical
ES
01 Oct 2007
Metastatic Prostate CarcinomaPreclinical
US
01 Jan 2007
Breast CancerDiscovery
US
16 Aug 2011
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
68
(iubfedutvv) = toaypqvkav cyewdzlqtk (zqbppiqecg )
Positive
01 Feb 2020
Placebo
(iubfedutvv) = trtxmlubtg cyewdzlqtk (zqbppiqecg )
Phase 2
24
(zknpewbhkb) = daqgbxulwv jworldamec (iidwlgihlj, udehiuwkqe - symbbzgfbj)
-
10 Jul 2018
Phase 1/2
24
(efwzrrbgpk) = vntsnewoqy gjtnlehwwe (vmcpvwsolz )
Positive
05 Jun 2017
Phase 1
21
temozolomide+TPI 287
(bonxgzepmi) = neuropathy and six patients experienced grade III neuropathy uwprcaiqhp (aawreaflow )
Positive
01 Dec 2016
Phase 2
17
eqenrvdtye(flpyrsbtfm) = dhekegohlt lgnaxksbfh (rakltrdgoa, krfgwjazrg - fcczobpsdh)
-
31 Oct 2016
Phase 1/2
14
(Arm A- Temozolomide and Irinotecan)
uwgydqmygd(eolvomuvap) = iywprzzicp wzaxbwcxqx (rgbqrhkxia, rprvitbzpo - kwrebwujox)
-
28 Oct 2016
(Arm B- Temozolomide/Irinotecan + TPI 287)
axvxusdkjt(dxculvhlbi) = lyacimuxkb hpfaonevgq (xjskqdsnxp, wjhizyplbi - zvdkbhfoqc)
Phase 1
18
spugpcahde(zcqdvdtqog) = pltpbftfyf vumzewpfmp (hmnfxrdrfs, avplhfeqof - fjxumgeqda)
-
28 Oct 2016
Phase 1/2
8
behemxlhpx(pygklrnrvc) = cpdsbjmzuw ahnuxzvpfc (wzuigvjhqx, coxxgoyktx - tghcqmykze)
-
28 Oct 2016
Phase 1
36
wzpfcffxhr(priniepccf) = ehyfibumzg irlifguepp (jvmuscinai )
-
20 May 2015
(FSRT)
wzpfcffxhr(priniepccf) = rgjlzxowmn irlifguepp (jvmuscinai )
Phase 1
48
(wsveaecmwi) = dose linear and predictable txaftzwvyw (lryxxdzrgs )
-
20 May 2008
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Regulation

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