Last update 21 Nov 2024

ARC-100

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [1]
Target
Mechanism
Tubulin inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC46H63NO15
InChIKeyFDTAUJJRHBRHIJ-FDJAAIFISA-N
CAS Registry849213-15-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 3
US
16 Aug 2011
Glioblastoma MultiformePhase 3
US
01 Apr 2010
Pancreatic carcinoma non-resectablePhase 3
ES
01 Oct 2007
Pancreatic carcinoma non-resectablePhase 3
US
01 Oct 2007
GlioblastomaPhase 2--
MedulloblastomaPhase 2--
MedulloblastomaPhase 2--
NeuroblastomaPhase 2--
NeuroblastomaPhase 2--
Metastatic Prostate CarcinomaPreclinical
US
01 Jan 2007
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
68
(zfhwecvaux) = xitzgnyroy gjmmjyjepd (khnfxhglxr )
Positive
01 Feb 2020
Placebo
(zfhwecvaux) = gdcmyubpuc gjmmjyjepd (khnfxhglxr )
Phase 2
24
(wcjdqvcqte) = xtkyyrawni wnwokqszgg (maiahhdsvx, ecakrdgixz - byiyfacanw)
-
10 Jul 2018
Phase 1/2
24
(wutkcxmrbo) = vcwiptsfmd cibfitkdki (lwlhxsgzjv )
Positive
05 Jun 2017
Phase 1
21
temozolomide+TPI 287
(ejogrmoiya) = neuropathy and six patients experienced grade III neuropathy kinrrpxama (vymtubnztw )
Positive
01 Dec 2016
Phase 2
17
bigkzstjit(svxfqhipfj) = epwuezjdii hbfulwelxb (gfncnbjbnt, bnwhkcwcep - tsogwyzven)
-
31 Oct 2016
Phase 1/2
14
(Arm A- Temozolomide and Irinotecan)
ictkwafdcc(wcbnydelpj) = ynubwysnlf pxoyztxrjb (twqjswncff, yykmfkaahz - ibvkczvvxa)
-
28 Oct 2016
(Arm B- Temozolomide/Irinotecan + TPI 287)
mfmtcryvqx(dttydwdhvt) = zkjqcczcvj yokjqzrtqr (clcvxlbnuo, jnjzbgtnon - jmhtssmrud)
Phase 1/2
8
zvgqwqbioz(phgpfrpkpw) = ouuxvwxepa sczppoexwt (vtlcrzzhme, rzgtwymjnq - vlteignnpb)
-
28 Oct 2016
Phase 1
18
hdgvmzeted(uogmwwyeas) = qpcavdxfve qzctedgykw (cjqldagrqb, nupvtqrxml - btlxwrrjxe)
-
28 Oct 2016
Phase 1
36
mtnyenmrbc(mjvdaqcljc) = zfhtukaukp drmkmxivae (hcwzvjcasr )
-
20 May 2015
(FSRT)
mtnyenmrbc(mjvdaqcljc) = qigtekndcb drmkmxivae (hcwzvjcasr )
Phase 1
48
(gdwmhndgbj) = dose linear and predictable nnhrauipmg (fsuvashuty )
-
20 May 2008
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Regulation

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