Last update 01 Nov 2024

AP-306

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [3]
Mechanism
NaPi-2b inhibitors(Sodium-dependent phosphate transport protein 2B inhibitors), P-gp inhibitors(P-glycoprotein 1 inhibitors), SLC20A1 inhibitors(solute carrier family 20 member 1 inhibitors)
+ [1]
Inactive Indication-
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationBreakthrough Therapy (CN)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPhase 2
CN
20 Feb 2023
HyperphosphatemiaPhase 2
CN
20 Feb 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
55
(yovzhfdxzn) = jqjbintnuu duhldqvkfj (itybrpezpz, -3.07~-1.92)
Positive
27 May 2024
(yovzhfdxzn) = dyxcvtkmsl duhldqvkfj (itybrpezpz, -1.58~-0.59)
Phase 2
55
(fkeymccuas) = At the end of treatment, the effect size of serum phosphorus reduction from baseline for AP306 was clinically significant tcstjqeqcr (pttvnwsesq )
Positive
13 Dec 2023
Phase 1
-
-
icqonwqthi(atknfnzknm) = Eight patients had gastrointestinal disorders (2 patients in each group) ygcxkemaev (fspfuqtyby )
Positive
05 Nov 2019
Placebo
Not Applicable
-
fsbbibazhg(nsbmdtzxqh) = sbkgepgouk mysfnctuxn (ckngaqoxjr )
Positive
23 Oct 2018
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Regulation

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