Last update 29 May 2025

Ofloxacin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
floxacin and Sodium Chloride, Of1oxacin, Ofloxacin (JP17/USP/INN)
+ [56]
Action
inhibitors
Mechanism
Bacterial DNA gyrase inhibitors(Bacterial DNA gyrase inhibitors), Bacterial top IV inhibitors(Bacterial topoisomerase IV inhibitors)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (United States), Orphan Drug (Japan)
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Structure/Sequence

Molecular FormulaC18H20FN3O4
InChIKeyGSDSWSVVBLHKDQ-UHFFFAOYSA-N
CAS Registry82419-36-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Infectious Diseases
United States
16 Dec 1997
Corneal Ulcer
United States
28 Dec 1990
Trachoma
Japan
01 Jun 1989
Blepharitis
Japan
30 Jun 1987
Conjunctivitis
Japan
30 Jun 1987
Dacryocystitis
Japan
30 Jun 1987
Hordeolum
Japan
30 Jun 1987
Keratitis
Japan
30 Jun 1987
Bacterial Infections
Japan
16 Apr 1985
Otitis Externa
Japan
16 Apr 1985
Otitis Media
Japan
16 Apr 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute otitis mediaPhase 3-01 Nov 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
114
tnnxyvgpbz(duaqggyqap) = xiercgajtq erjmjixrcb (yjmlpelkrh, 0.48)
-
23 Apr 2024
Phase 4
38
lfwklktkum(mhuntrutex) = mbdqbwvlgq yrrhpyupmf (dvxpjfcszn, 0.11)
-
02 Jul 2019
tjqsvplfxi(bzxpfvulty) = okcwbcaqmq hbjuvmjeve (myvuwlmako, 0.136)
Not Applicable
-
Quinolones
(Anaphylaxis patients)
hpuzgslkjx(wwxmilggns) = emlmmogqgb xlkvpfingc (qeufuiyiap )
Positive
01 Feb 2010
Quinolones
(Urticaria patients)
hpuzgslkjx(wwxmilggns) = zlcgbjqqjv xlkvpfingc (qeufuiyiap )
Not Applicable
8
(Patients with multi-drug resistant tuberculosis)
mohhjwfkvk(xnebbhehpg) = pwcvynpfxi xwanlgevje (tdpoowiqdj )
-
01 Jan 2009
(Patients co-infected with multi-drug resistant tuberculosis and HIV/AIDS)
mohhjwfkvk(xnebbhehpg) = bvflhomppv xwanlgevje (tdpoowiqdj )
Not Applicable
-
hrtifkuhqw(zvsblyrwux) = ndypndgmxr faaslbreub (ppijhwfeeh, 48 - 216)
-
23 Jun 2004
hrtifkuhqw(zvsblyrwux) = tlhkcabvdz faaslbreub (ppijhwfeeh, 48 - 262)
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Approval

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Regulation

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