Last update 19 Jul 2025

Lomibuvir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lomibuvir (USAN/INN), VCH-222, VX-222
Action
inhibitors
Mechanism
NS5B polymerase inhibitors(Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC25H35NO4S
InChIKeyWPMJNLCLKAKMLA-VVPTUSLJSA-N
CAS Registry1026785-55-6

External Link

KEGGWikiATCDrug Bank
D10425--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
FibrosisPhase 2
United States
01 Feb 2012
FibrosisPhase 2
Canada
01 Feb 2012
FibrosisPhase 2
Germany
01 Feb 2012
FibrosisPhase 2
Poland
01 Feb 2012
FibrosisPhase 2
United Kingdom
01 Feb 2012
Chronic hepatitis C genotype 1Phase 2
United States
01 Aug 2010
Chronic hepatitis C genotype 1Phase 2
New Zealand
01 Aug 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
152
osxndomizc(pokwmrzvqz) = osvcqukael isgmglkeui (dueovajedh )
-
01 Jul 2014
osxndomizc(pokwmrzvqz) = jtceohmvil isgmglkeui (dueovajedh )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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