Last update 22 Dec 2024

Teprasiran

Overview

Basic Info

Drug Type
siRNA
Synonyms
DGFi, Teprasiran sodium, AKII-5
+ [4]
Target
Mechanism
P53 gene stimulants
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Kidney InjuryPhase 3
US
29 Jun 2018
Acute Kidney InjuryPhase 3
AU
29 Jun 2018
Acute Kidney InjuryPhase 3
AT
29 Jun 2018
Acute Kidney InjuryPhase 3
BE
29 Jun 2018
Acute Kidney InjuryPhase 3
CA
29 Jun 2018
Acute Kidney InjuryPhase 3
CZ
29 Jun 2018
Acute Kidney InjuryPhase 3
FR
29 Jun 2018
Acute Kidney InjuryPhase 3
DE
29 Jun 2018
Acute Kidney InjuryPhase 3
NZ
29 Jun 2018
Acute Kidney InjuryPhase 3
ES
29 Jun 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
341
awjnpnjkks(whhcjjpxzg) = cfzyogmsbg rzqfeldaim (janzomnjck )
Positive
05 Oct 2021
Placebo
awjnpnjkks(whhcjjpxzg) = egdpjkbrye rzqfeldaim (janzomnjck )
Phase 2
Acute Kidney Injury
SCysC | SCr | eGFRCys ...
341
ujtjbtemel(mjxnetrfxw) = otddybolvc vexfqswcra (sqvylppeqo )
Positive
23 Oct 2018
Placebo
ujtjbtemel(mjxnetrfxw) = lahvxokffy vexfqswcra (sqvylppeqo )
Phase 1
16
faujrjmvvi(dmnakflwai) = pxbadtbctr wxdgfqwgxg (aknsscwqpv )
Positive
25 Apr 2017
Placebo
faujrjmvvi(dmnakflwai) = ychsfponwb wxdgfqwgxg (aknsscwqpv )
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Approval

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Regulation

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