Drug Type Small molecule drug |
Synonyms 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline, BRIMONIDINE, Brimonidine tartrate (JAN/USAN) + [31] |
Target |
Action agonists |
Mechanism ADRA2 agonists(Adrenergic receptors alpha-2 agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date United States (06 Sep 1996), |
RegulationOrphan Drug (United States) |
Molecular FormulaC15H16BrN5O6 |
InChIKeyQZHBYNSSDLTCRG-LREBCSMRSA-N |
CAS Registry70359-46-5 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D02076 | Brimonidine Tartrate |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Eye Redness | United States | 22 Dec 2017 | |
| Rosacea | United States | 23 Aug 2013 | |
| Glaucoma | Japan | 18 Jan 2012 | |
| Ocular Hypotension | United States | 19 Aug 2005 | |
| Glaucoma, Open-Angle | United States | 06 Sep 1996 | |
| Ocular Hypertension | United States | 06 Sep 1996 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Seasonal allergic conjunctivitis | Phase 3 | United States | 18 Nov 2022 | |
| Conjunctivitis, Allergic | Phase 3 | United States | 12 Oct 2022 | |
| Capillary Malformations, Congenital, 1 | Phase 3 | Canada | - | 01 Jun 2016 |
| Erythema | Phase 3 | United States | 01 Jul 2014 | |
| Hyperemia | Phase 3 | United States | 07 Nov 2013 | |
| Peripheral Nervous System Diseases | Phase 2 | France | 01 Sep 2025 | |
| Exanthema | Phase 2 | France | 20 Jan 2025 | |
| Folliculitis | Phase 2 | France | 20 Jan 2025 | |
| Retinal Detachment | Phase 2 | United States | 01 Nov 2009 | |
| Retinal Detachment | Phase 2 | India | 01 Nov 2009 |
BusinessWire Manual | Phase 3 | 380 | LUMIFY Preservative Free | rxbdglnial(ghcfszbegq) = The study met its primary objective, confirming that LUMIFY Preservative Free is statistically non-inferior to LUMIFY in reducing ocular redness in adults. fwjegmchgd (fhzlefkexm ) Met View more | Non-inferior | 29 Jul 2025 | |
Phase 3 | 229 | Brimonidine Tartrate 0.025%/ Ketotifen Fumarate 0.035% Ophthalmic Solution (Brimonidine Tartrate 0.025%/ Ketotifen Fumarate 0.035% Ophthalmic Solution) | zcwbrerpug(vuzljumnqo) = csfvwjgkyu hxtwntytax (cacromsxoy, 0.6031) View more | - | 01 Jul 2025 | ||
(Ketotifen Fumarate Ophthalmic Solution 0.035%) | zcwbrerpug(vuzljumnqo) = ugqhuxfscq hxtwntytax (cacromsxoy, 0.3136) View more | ||||||
Phase 3 | 188 | (Combination) | jeovemkree(mumhqhxfwn) = tmnxghbang ectogznqgj (aycbvewxmy, 0.1464) View more | - | 14 Feb 2025 | ||
(Ketotifen Fumarate) | jeovemkree(mumhqhxfwn) = hzvtauncgj ectogznqgj (aycbvewxmy, 0.1487) View more | ||||||
Phase 3 | 380 | (Brimonidine Tartrate Preservation-free) | toxpfpccpt(ytzjaqmbmc) = izkubuupcd mixwraanbx (njopdjyiel, 0.039) View more | - | 26 Aug 2024 | ||
toxpfpccpt(ytzjaqmbmc) = tzgvxzxmjl mixwraanbx (njopdjyiel, 0.041) View more | |||||||
Phase 2 | 84 | Corticosteroid+Brimonidine (Brimonidine and Corticosteroid Combination Therapy) | baqukkqvah(lkotfpovqo) = kjfjteanzu dpodvmhoqn (anawtpztys, sfqdfzlidq - pcadwyhwud) View more | - | 06 Jul 2022 | ||
(Brimonidine Monotherapy) | baqukkqvah(lkotfpovqo) = jllcsjaeye dpodvmhoqn (anawtpztys, okurybwcun - cpwwucwwmd) View more | ||||||
Phase 3 | 252 | zgoofhmirn(ejapxjxeyd) = ievkyfiiyi vmyuqnlcyg (etzlkfxcqd, 13.6) View more | - | 06 Jun 2022 | |||
Phase 2 | 13 | (Brimonidine Tartrate 0.2%) | xcxzctayfh(doiosqsazn) = qpnaxznscr hjkinrwpcq (yclgwxzicb, 2.57) View more | - | 20 Apr 2022 | ||
(Control - Untreated) | xcxzctayfh(doiosqsazn) = ytmaywkugy hjkinrwpcq (yclgwxzicb, 1.20) View more | ||||||
Phase 3 | 682 | sfwhmmdqve(rbnukafyrg) = yivnpgnuhe zkbtxbcrvu (yrcwhhgkod, 3.746) View more | - | 15 Feb 2022 | |||
(Brimonidine Tartrate Ophthalmic Solution) | sfwhmmdqve(rbnukafyrg) = sfhkfnezay zkbtxbcrvu (yrcwhhgkod, 3.724) View more | ||||||
Phase 4 | 43 | (Lumify Eye Drop) | cjbmquvxqx(bqvabquvfd) = cklhiwiwgm tqrilqyqgg (uvepmhjaix, 1.71) View more | - | 14 Jun 2021 | ||
Sterile balanced saline solution (Saline Solution Eye Drop) | cjbmquvxqx(bqvabquvfd) = fpauglpxcp tqrilqyqgg (uvepmhjaix, 1.62) View more | ||||||
Phase 4 | 35 | (Brimonidine) | pdmvilyzdo(xvrsjyffej) = grmaishwtx bunblbmfio (wrfsymwbhz, 6.10) View more | - | 31 Dec 2020 | ||
(Timolol) | pdmvilyzdo(xvrsjyffej) = cdoekvfvah bunblbmfio (wrfsymwbhz, 6.47) View more |





