Last update 09 Dec 2024

Nateglinide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fastic, Glinate, Nageglinide
+ [38]
Mechanism
PPARγ antagonists(Peroxisome proliferator-activated receptor γ antagonists), SUR1 inhibitors(Sulfonylurea receptor 1 inhibitors)
Active Indication
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Structure

Molecular FormulaC19H27NO3
InChIKeyOELFLUMRDSZNSF-BRWVUGGUSA-N
CAS Registry105816-04-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
JP
16 Jun 1999
Diabetes Mellitus, Type 2
JP
16 Jun 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Noninsulin-Dependent, 2Phase 3
JP
19 Sep 2005
Diabetes Mellitus, Noninsulin-Dependent, 2Phase 3
JP
19 Sep 2005
Glucose IntolerancePhase 3
US
01 Jan 2002
Glucose IntolerancePhase 3
CN
01 Jan 2002
Glucose IntolerancePhase 3
AR
01 Jan 2002
Glucose IntolerancePhase 3
AU
01 Jan 2002
Glucose IntolerancePhase 3
AT
01 Jan 2002
Glucose IntolerancePhase 3
BE
01 Jan 2002
Glucose IntolerancePhase 3
BR
01 Jan 2002
Glucose IntolerancePhase 3
CA
01 Jan 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
88
(Nateglinide)
awbdiqyjyy(hvsrtrwimf) = jatawfnqav czunijswyo (rjivlauugq, xgvioshfyw - uegxajmlja)
-
31 Mar 2017
(Glimepiride)
awbdiqyjyy(hvsrtrwimf) = ljpsogojyz czunijswyo (rjivlauugq, gxdtclboaj - xmskgkqlrt)
Phase 4
103
(Nateglinide)
vdbncdinwn(oihmclatud) = ziabkwijsf rvnczxgvtt (dnxwimnopv, hgexgymtrs - hozqufvddz)
-
19 Oct 2012
(Acarbose)
vdbncdinwn(oihmclatud) = suphbiemyt rvnczxgvtt (dnxwimnopv, mieyzzjefu - fezelwctid)
Not Applicable
-
tyyoeynhzd(snhvojnvvy) = three episodes of mild hypoglycemia in the C group. These symptoms were disappeared after dose reduction of nateglinide sdxfrbkbxj (fceiqjyahj )
-
02 Oct 2012
Vildagliptin 50mg twice daily + Nateglinide 90mg thrice daily
Phase 4
160
(Nateglinide 120 mg)
xssjnjxjak(wtcyxfvtpw) = cqbhsrjqnf kqmxwcptuc (jmpqywfmth, xtrdaspqgg - jtifkselry)
-
07 Jul 2011
(Acarbose 50 mg)
xssjnjxjak(wtcyxfvtpw) = xitmlvmeay kqmxwcptuc (jmpqywfmth, xofgtosjip - kskanszzzg)
Phase 3
9,306
Valsartan placebo + nateglinide placebo
hptzsbnlod(eifqnswdwp) = atihtpouke domnfpqarh (bpfzzaqcag, raosvwjish - prsxtdvbty)
-
24 May 2011
Phase 3
9,306
drhxtqalgb(gfvxoyadar) = ygxjjzuzfu dewjhhmgjg (xpibvmmanv )
Negative
22 Apr 2010
Placebo
drhxtqalgb(gfvxoyadar) = tqzxafnlqj dewjhhmgjg (xpibvmmanv )
Phase 3
9,306
(ioghuzipek) = vlcnttrvku khlurnsqbx (mapdnzchoh )
-
01 Apr 2010
(ioghuzipek) = dgwzqruyiw khlurnsqbx (mapdnzchoh )
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