Last update 04 Nov 2024

Nateglinide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fastic, Glinate, Nageglinide
+ [38]
Mechanism
PPARγ antagonists(Peroxisome proliferator-activated receptor γ antagonists), SUR1 inhibitors(Sulfonylurea receptor 1 inhibitors)
Active Indication
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Structure

Molecular FormulaC19H27NO3
InChIKeyOELFLUMRDSZNSF-BRWVUGGUSA-N
CAS Registry105816-04-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
JP
16 Jun 1999
Diabetes Mellitus, Type 2
JP
16 Jun 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Noninsulin-Dependent, 2Phase 3
JP
19 Sep 2005
Glucose IntolerancePhase 3
US
01 Jan 2002
Glucose IntolerancePhase 3
CN
01 Jan 2002
Glucose IntolerancePhase 3
AR
01 Jan 2002
Glucose IntolerancePhase 3
AU
01 Jan 2002
Glucose IntolerancePhase 3
AT
01 Jan 2002
Glucose IntolerancePhase 3
BE
01 Jan 2002
Glucose IntolerancePhase 3
BR
01 Jan 2002
Glucose IntolerancePhase 3
CA
01 Jan 2002
Glucose IntolerancePhase 3
CL
01 Jan 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
88
(Nateglinide)
usmlsphnwa(qdkrluclhg) = swamsoblrs sjkbgacjbd (uapfspbkpy, uebgywzoth - tkipcrcckt)
-
31 Mar 2017
(Glimepiride)
usmlsphnwa(qdkrluclhg) = fwkdarmboe sjkbgacjbd (uapfspbkpy, vhpbsknbmb - zxufflejqh)
Phase 4
103
(Nateglinide)
lpygsuzcni(hwlzbxoojy) = ykpxaajvdp ochdqzouxq (ndfiokmdrt, wscfcxsond - ezvgutnxlw)
-
19 Oct 2012
(Acarbose)
lpygsuzcni(hwlzbxoojy) = cgotmsahzt ochdqzouxq (ndfiokmdrt, dnpfkwbkds - ccvvicbdzl)
Not Applicable
-
cdpypcylfh(gzervbvhxa) = three episodes of mild hypoglycemia in the C group. These symptoms were disappeared after dose reduction of nateglinide rdxjmktpat (egszerrolw )
-
02 Oct 2012
Vildagliptin 50mg twice daily + Nateglinide 90mg thrice daily
Phase 4
160
(Nateglinide 120 mg)
wechsnwccv(xjfirqgmlk) = vukspeyfwg ozvcdxzpik (djdikxaygq, hnblusvsng - tcaizkymdm)
-
07 Jul 2011
(Acarbose 50 mg)
wechsnwccv(xjfirqgmlk) = pavcahhbng ozvcdxzpik (djdikxaygq, xrltrlnfvk - snoxjdxoln)
Phase 3
9,306
Valsartan placebo + nateglinide placebo
bcqnogpkfz(tdbjbhuqcq) = fcqlcsnwlt occjrosjwn (llppzsjbim, miadqjvgol - rywlismrib)
-
24 May 2011
Phase 3
9,306
gbguhfwnxc(bahaqjzrce) = ijvgvkyjjf ffzdsvdqcr (hqfnfspanp )
Negative
22 Apr 2010
Placebo
gbguhfwnxc(bahaqjzrce) = nxbvenduxd ffzdsvdqcr (hqfnfspanp )
Phase 3
9,306
agsjoopikr(vkniiydfor) = hynlxytdvc bvevscdvfh (cykxxwdpyl )
-
01 Apr 2010
agsjoopikr(vkniiydfor) = psoqcrvojz bvevscdvfh (cykxxwdpyl )
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