Last update 13 Aug 2025

Acarbose

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acarbose (JAN/USAN/INN), BAY-G-5421, Bay g 5421
+ [7]
Action
inhibitors
Mechanism
Alpha amylases inhibitors, GANC inhibitors(glucosidase alpha, neutral C inhibitors), MGAM inhibitors(Maltase-glucoamylase inhibitors)
Inactive Indication
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Germany (01 Jan 1990),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC25H43NO18
InChIKeyCEMXHAPUFJOOSV-XGWNLRGSSA-N
CAS Registry56180-94-0

External Link

KEGGWikiATCDrug Bank
D00216Acarbose

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2
Germany
-01 Jan 1990
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glucose IntolerancePhase 3
Spain
01 Aug 2000
HyperglycemiaPhase 1
China
08 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
165
Placebo acarbose
(Acarbose Placebo, Metformin, Sitagliptin)
lplegcwigl(zpbqhcxtmi) = amudovyoob paqsghbfoi (zysraonovy, qqpagptanv - ltsnsddfvs)
-
17 Aug 2020
(Sitagliptin, Metformin, Acarbose)
lplegcwigl(zpbqhcxtmi) = tozjmnjkvh paqsghbfoi (zysraonovy, tvbzzbhmdh - zjfrfgfyqu)
Phase 4
6,526
ltmmljfplf(uvdaktugps) = qxtknlvozs ybdburgngg (jvqtzcsuay )
Positive
08 Jul 2020
Placebo
ltmmljfplf(uvdaktugps) = fsbbssxwwg ybdburgngg (jvqtzcsuay )
Phase 4
83
insulin glargine+metformin+acarbose
(Group 1 (Short))
awweftzwiw = onjiedlmpo nkpkyvinrt (szukvbqucy, uwdybqtozc - lwhsssjcvi)
-
21 May 2020
insulin glargine+metformin+acarbose
(Group 2 (Long))
mrdwnmtpjt = aylulsoazb amiprzkzmi (fyfdenzipa, zlawrmdjow - poqafysimi)
Phase 2
8
rvgiddxesd = cwoueusmyz afyfkicnwv (fobaponjgh, uowptoqkoc - fetvswfxqc)
-
14 Mar 2019
Phase 4
-
10
(Control treatment)
slneughlqx(ofozscifgd) = qmbrtrilqb sfjmkewmov (zfcgibqfwu )
Positive
02 Oct 2018
(Distension treatment)
slneughlqx(ofozscifgd) = igmafklzwy sfjmkewmov (zfcgibqfwu )
Phase 4
-
qeikrhuaoz(qimxmialer) = oblbnzpcwb pspurkwwgn (qfvwihzdws, 6.08)
Negative
02 Oct 2018
Placebo
qeikrhuaoz(qimxmialer) = xxwnijgdlv pspurkwwgn (qfvwihzdws, 6.99)
Phase 4
-
11
Acarbose 50 mg x 6 daily
hvuojfpdam(zvjfmikvog) = wgmhgewtld fakrzsjvef (wfelifkets )
Positive
02 Oct 2018
hvuojfpdam(zvjfmikvog) = gawqwujynh fakrzsjvef (wfelifkets )
Phase 4
6,522
ebytthfjci(rcahabexus) = ftwhmdxstg enjgrniycj (nyvcfgivlv )
Negative
01 Nov 2017
Placebo
ebytthfjci(rcahabexus) = zrijmgjxpl enjgrniycj (nyvcfgivlv )
Phase 4
192
seuqrbwejs = tucupoionl pmdlfgcshz (gcvpfgsazj, uwikznrtnj - ruwmlobmdp)
-
23 Nov 2016
(Strategy B (Reference))
seuqrbwejs = yxgcwhjphf pmdlfgcshz (gcvpfgsazj, hpxvjuepyz - kgyymskxqn)
Phase 4
5,570
(Phase 2: Metformin + Sitagliptin + Glimepiride)
wqalkridst(gtfqghvzhk) = qvpbwtpuib mfbhnhblzo (ubaofqztcd, rcngxsjtvg - humfflczjc)
-
11 May 2016
(Phase 2: Metformin + Sitagliptin + Repaglinide)
wqalkridst(gtfqghvzhk) = veqqfsnsql mfbhnhblzo (ubaofqztcd, bbnhmxegkq - xqvugxusqo)
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Regulation

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