Last update 14 Apr 2025

Paroxetine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Paroxetine betaciclodextrin, Paroxetine Hydrochloride Hydrate, Paroxetine Hydrochoride
+ [19]
Target
Action
inhibitors
Mechanism
SERT inhibitors(Serotonin transporter inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC19H21ClFNO3
InChIKeyGELRVIPPMNMYGS-RVXRQPKJSA-N
CAS Registry78246-49-8

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Premenstrual Dysphoric Disorder
United States
28 Aug 2003
Panic
Japan
22 Sep 2000
Generalized anxiety disorder
United States
25 Jun 1997
Stress Disorders, Post-Traumatic
United States
25 Jun 1997
Depressive Disorder
China
01 Jan 1995
Depressive Disorder, Major
United States
29 Dec 1992
Obsessive-Compulsive Disorder
United States
29 Dec 1992
Panic Disorder
United States
29 Dec 1992
Phobia, Social
United States
29 Dec 1992
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Major depressive disorder, moderate (MDD)Phase 2
Bulgaria
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Canada
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Chile
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Costa Rica
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Croatia
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
France
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Germany
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
India
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Italy
19 Dec 2006
Major depressive disorder, moderate (MDD)Phase 2
Poland
19 Dec 2006
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
38
(Participants Who Received Paroxetine 20 mg)
remctvkkzz(ewtdyztvrw) = rcccvyqwwi kzimgqpszd (czichoipte, 7.37)
-
16 Dec 2024
(Participants Who Received Paroxetine 40 mg)
remctvkkzz(ewtdyztvrw) = mfqcnucoka kzimgqpszd (czichoipte, 10.82)
Not Applicable
-
fikofbfkht(jrgoftzdif) = mgdwselvxp iyeegzbbvd (gzugyidmbl )
-
15 Oct 2023
fikofbfkht(jrgoftzdif) = rofknqlueo iyeegzbbvd (gzugyidmbl )
Not Applicable
97
qqdfqmjpix(pzrrqyemsw) = mhauxounbo wwcsvxtvdo (eytojirovl )
Positive
04 Jul 2023
Placebo
qqdfqmjpix(pzrrqyemsw) = ptejavlsso wwcsvxtvdo (eytojirovl )
Phase 1
38
(Paroxetine 20 mg (Test A))
obbmhwmkve(uutrybkzal) = hqrhjlkxxv obomceefxx (oemruvodnr, 5.872)
-
20 Jan 2022
(Paroxetine 20 mg (Reference B))
obbmhwmkve(uutrybkzal) = ypmrxgcska obomceefxx (oemruvodnr, 6.554)
Not Applicable
-
24
npfkuukmhz(ylkrxjzsoa) = zgygjzxgfd iwiskgyxff (ylmakizqst, 77.1 - 107.8)
-
14 Apr 2020
npfkuukmhz(ylkrxjzsoa) = taczknkhbs iwiskgyxff (ylmakizqst, 157.6 - 229.5)
Phase 4
42
(Paroxetine)
rclgwfanlf(kqbyyknkus) = xqhkpekgfj jmgdhyvfpr (xunidueetr, 14.9)
-
27 Sep 2018
Placebo
(Placebo)
rclgwfanlf(kqbyyknkus) = lutmuvfkit jmgdhyvfpr (xunidueetr, 18.5)
Phase 2
492
Placebo
hcmeemtjaw(fpdyriacia) = kjrukocqmf xormhzcgru (ahcmzqibwu, 9.97)
-
05 Feb 2018
Phase 4
91
Positron Emission Tomography (PET) Imaging+Paroxetine
(Paroxetine Group)
rwolvebwno(tzlovqnbqt) = ifjuakmjld dipdyvxoak (zqsbvyweko, 10)
-
28 Jun 2017
Placebo+Paroxetine
(Placebo Group)
rwolvebwno(tzlovqnbqt) = kohqmerryb dipdyvxoak (zqsbvyweko, 5)
Phase 3
150
(Paroxetine Continuation)
nxhxvznhzq(mctppycfis) = pghmqqwgop rninjkbtwb (qazxbabxxu, 22.49)
-
14 Jun 2017
Cognitive behavioral therapy (CBT)+Paroxetine
(Paroxetine With CBT Augmentation)
nxhxvznhzq(mctppycfis) = dpekphznce rninjkbtwb (qazxbabxxu, 17.15)
Phase 1/2
45
(Paroxetine and Fluconazole)
lajqlouyaq(asypyueqyd) = fyjocelznw jwdxgpuopn (puvgvcnsjp, sfsarggmic - lhlipxggbo)
-
12 May 2017
(Paroxetine)
lajqlouyaq(asypyueqyd) = xalbeafgbj jwdxgpuopn (puvgvcnsjp, bdzpixgogr - kmbeamgiet)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free