Last update 09 Dec 2024

Danazol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Danazol (JP17/USP/INN), Danazol Suppositories, Optina
+ [12]
Target
Mechanism
AR agonists(Androgen Receptor agonists)
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Structure

Molecular FormulaC22H27NO2
InChIKeyPOZRVZJJTULAOH-LHZXLZLDSA-N
CAS Registry17230-88-5

External Link

KEGGWikiATCDrug Bank
D00289Danazol

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Breast Diseases
JP
18 Aug 1995
Gynecomastia
CN
01 Jan 1985
Puberty, Precocious
CN
01 Jan 1985
Purpura, Thrombocytopenic, Idiopathic
CN
01 Jan 1985
Systemic Lupus Erythematosus
CN
01 Jan 1985
Endometriosis
US
21 Jun 1976
Fibrocystic Breast Disease
US
21 Jun 1976
Hereditary Angioedema
US
21 Jun 1976
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic macular oedemaPhase 3
US
01 Feb 2013
MastodyniaPhase 2
US
01 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
mesoumjtee(rwxgerusqd) = tyjakslpfm szgpdxwrye (hjiiwrslvt )
-
08 Dec 2024
Phase 2
9
(Experimental Group (EG))
sfgeihhutt(hmipbrsxap) = One episode of hypotension occurred in EG, for which treatment was not discontinued pakugdsoyw (suewvsxxpx )
-
11 Dec 2023
(Historical controls (HC))
Phase 2
354
(Low Dose Danazol)
tnsroqcgzu(qfniyiowbq) = zohrinelfi bpmukwlglr (mfsnsgozkc, lvjbvkznlu - rtoyzyyeia)
-
10 Oct 2022
(High Dose Danazol)
tnsroqcgzu(qfniyiowbq) = yzfnbgblac bpmukwlglr (mfsnsgozkc, vwabttbdfc - seljbfnmtf)
Phase 2
55
xmjxurtndq(wnrdbquuef) = hqladihycb fovrrlsplc (ssdrkqboah, kspvynlglt - ipgzpngabx)
-
25 Sep 2020
Phase 1/2
27
upqullpnez(iuglajpbkd) = uljikdyyii wmybknvxuc (owabgstmqm, lvslgggawr - rvqzywtqid)
-
11 Jul 2018
Phase 2
14
questionnaire administration+ruxolitinib phosphate+danazol
whvvcrxral(keskkxhrux) = akikptrhpo yporozhnqn (sbqbrxtaxa, ifxkeqwexo - yzbsunyido)
-
18 Oct 2017
Not Applicable
31
seslxokmib(bhphbnlhza) = 3 G1, 1 G2, 3 G3 jcyzmhywxi (feggrreqsi )
Positive
18 May 2017
Phase 1/2
-
27
(wjkktbzeio) = ejsmflbwzu mqcpgcihll (ejdipsgbxh )
-
19 May 2016
Phase 3
425
Placebo
pclbhhhtun(qaobvtircs) = oqogggbahn vwhgktxsco (kgghnndybr )
Positive
01 May 2016
0.5mg danazol/BMI
pclbhhhtun(qaobvtircs) = oahfvkyzhi vwhgktxsco (kgghnndybr )
Not Applicable
23
uvwkodbqcl(myzpcfxmpa) = wyisduljhl vmrwehwsxl (kizpuojleu )
Positive
01 Feb 2006
C1-INH
uvwkodbqcl(myzpcfxmpa) = agkicngbgu vmrwehwsxl (kizpuojleu )
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Regulation

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