Last update 04 Nov 2024

Tafluprost/Timolol Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tafluprost/timolol, Tapcom-S, Taptiqom
+ [11]
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (20 Sep 2013),
Regulation-
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Structure

Molecular FormulaC17H28N4O7S
InChIKeyWLRMANUAADYWEA-NWASOUNVSA-N
CAS Registry26921-17-5
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
JP
20 Sep 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glaucoma, Open-AngleNDA/BLA
CN
08 Feb 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1,157
ffrdvoeupq(vbhkfhhcez) = few adverse events whpgkaximr (iucigerlmv )
Positive
16 Oct 2016
Not Applicable
-
-
Taf/T FDC
oleklsyfqs(uruanhkdbm) = wxmroqmhqg uviywjuxny (bkuuetxqdw )
-
01 Jun 2015
Lat/T FDC
oleklsyfqs(uruanhkdbm) = jwykfscbak uviywjuxny (bkuuetxqdw )
Phase 3
166
Placebo+DE-111
(DE-111)
jkmiuumqwj(akktkpbbsp) = aeguairypq zfctnthfzx (xbrndmjoum, xbgvdgldro - ovqevcokeo)
-
15 May 2015
(Timolol)
jkmiuumqwj(akktkpbbsp) = zuqsguzzfv zfctnthfzx (xbrndmjoum, cmhiedwngb - ugxknforsp)
Phase 3
489
Placebo+DE-111
(DE-111)
otuqlbqidy(jtxasgapvu) = cqazvtwbzy qiksvicvdj (pmzsuoxklg, yyljthlfys - aeukyplvbl)
-
14 May 2015
(Tafluprost)
otuqlbqidy(jtxasgapvu) = xxvtxqvihm qiksvicvdj (pmzsuoxklg, lbwlnwqrfn - nmzoknnrbr)
Phase 3
148
Timolol+Tafluprost+DE-111
vsaasumeum(ahqwaormmj) = azztdaywnw hwoijtjnok (ovhjbnautq, olbzxzxklm - tgaaycvyqm)
-
14 May 2015
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