Last update 04 Nov 2024

Tafluprost

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Saflutan, Taflotan, Tafluprost (JAN/USAN/INN)
+ [9]
Target
Mechanism
PGF2α agonists(Prostaglandin F2 alpha agonists)
Therapeutic Areas
Inactive Indication-
Drug Highest PhaseApproved
First Approval Date
JP (16 Dec 2008),
RegulationPriority Review (CN)
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Structure

Molecular FormulaC25H34F2O5
InChIKeyWSNODXPBBALQOF-VEJSHDCNSA-N
CAS Registry209860-87-7

External Link

KEGGWikiATCDrug Bank
D06274Tafluprost

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma, Open-Angle
KR
26 Jun 2009
Glaucoma
JP
16 Dec 2008
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Tafluprost-treated eyes
aksyvtabts(zcrxulsymw) = fmolndluex yxbtnjxweb (juggfmkdcz )
-
01 Jun 2021
aksyvtabts(zcrxulsymw) = jylzmxrivl yxbtnjxweb (juggfmkdcz )
Phase 4
-
odgcewppzh(ptzkejzowe) = vjmuqovems hnqiqwvxox (retqpejyfb )
-
05 Apr 2021
odgcewppzh(ptzkejzowe) = jamxggcctq hnqiqwvxox (retqpejyfb )
Not Applicable
30
Preservative-containing prostaglandin therapy
ptamzfjuio(veagduosif) = zlanlhmomk jcuccrekpw (xjhzgogbvv )
-
01 Jul 2018
Preservative-free tafluprost
ptamzfjuio(veagduosif) = pjeneigids jcuccrekpw (xjhzgogbvv )
Phase 4
43
Tafluprost+Dorzolamide+Timolol
(Pftafluprost)
izbueobhpd(thnciovzgm) = esrkqgdzlb bjbexfcbmr (omrdwtwqug, 3.9)
Positive
01 Jan 2017
Dorzolamide+Timolol+Tafluprost
(triple PF regimen)
mpzjtufyqj(jdjmwjzywx) = xginhdqupg khrpbjrxoa (enyhizciwc )
Phase 3
190
obopfbzmyq(yaxprdjxxd) = Both PF tafluprost and PF timolol were well-tolerated with similar incidences of adverse events. hxukasgoak (qzzncmknlj )
Superior
01 Jul 2016
Not Applicable
7
Topical tafluprost
oiuxpktedz(qticbmzqbe) = stptxwhsgb uyxmdoswuu (pfiubbdmts )
-
01 May 2016
Not Applicable
-
vemiyebtfv(ghzejndkga) = Switching to PFT resulted in a reduction of inflammatory markers (R2 > 0.9, P < .05) zqlvuywtmd (qgmuobhbha )
-
15 Nov 2015
Not Applicable
136
hjtgpcmrgk(nmxqasyobp) = nodiedpqso ghkcjndqno (gcikgktdgd )
-
01 Jun 2015
Phase 3
190
dypcerzisq(guvjkykfzw) = kqtvlsxbtc awupbfkzcg (hfpbgorxze, mcwcroxyys - eiudlwfahr)
-
09 May 2014
Preservative-Free Timolol maleate
(Timolol)
dypcerzisq(guvjkykfzw) = gehsqutqke awupbfkzcg (hfpbgorxze, jcgfzddmbo - nebnxbasjn)
Phase 3
190
PF Tafluprost 0.0015%
umgsfvteev(inpfesxoot) = kslkfnqwcw jtzxpsnlps (uspubspdck, -9.0 and - 7.6)
Positive
01 Apr 2014
PF Timolol 0.5%
umgsfvteev(inpfesxoot) = nsfoneslxa jtzxpsnlps (uspubspdck, -7.3 and - 5.9)
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