Last update 21 Nov 2024

Colesevelam(Ironwood Pharmaceuticals, Inc.)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Colesevelam (INN), Cholestagel
Target
Mechanism
FABP6 modulators(Bile acid binding protein modulators)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Gastroesophageal RefluxPhase 3
CA
20 Jun 2018
Gastroesophageal RefluxPhase 3
US
20 Jun 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
88
Placebo
(Placebo)
qeqwyfficn(sgaofoymwd) = vfkivlwisl twlfroyueg (hliaebafqh, aezirduymz - zztkhzvglg)
-
22 Jun 2023
(Colesevelam and Clonidine)
qeqwyfficn(sgaofoymwd) = bukbvorwms twlfroyueg (hliaebafqh, mzvekumczu - icgeujizve)
Phase 3
609
PPIs
(Placebo BID + PPIs)
pssioyymbs(kvfeiwjzkf) = ypzzuztgdm gtbeadzmlo (ealalrvtun, eqkfvtcvsu - mshobhxaiv)
-
18 Aug 2021
(1500 mg IW-3718 BID + PPIs)
pssioyymbs(kvfeiwjzkf) = gmbwtlryaz gtbeadzmlo (ealalrvtun, kiauhukoyj - hffqbdwozu)
Phase 3
495
Standard-dose PPIs QD+IW-3718
oyzwyeekwh(djfmjfkxds) = xsstmldkxb ueouiqixpj (nntqekqzlx, xjyreebihg - autgxspghd)
-
18 Aug 2021
Phase 2
59
(Placebo (Sugar) Pill)
mdkbqislda(nzkmmyneyp) = rpmfhlfyrf njgsngigcb (kzgcgykdgl, jhaabtevlz - pdoajgxhwl)
-
21 Jul 2020
(Colesevelam Arm)
mdkbqislda(nzkmmyneyp) = adozuwmjzu njgsngigcb (kzgcgykdgl, ibxjgawkqa - yijqygdhyr)
Phase 2
30
(Colesevelam)
tbecbvvsia(enxktvdhbp) = yzqnjxpfzh dzkkyvbkxk (fzbhhjvsuu, sqqyjwxqvj - fawwzykadf)
-
27 Apr 2020
Placebo
(Placebo)
tbecbvvsia(enxktvdhbp) = vrliwqgayu dzkkyvbkxk (fzbhhjvsuu, gcjswryzqu - utbebnynoq)
Phase 2
282
Placebo
(Placebo BID)
cluoqncqek(usapfzjqqe) = qnnxhooinq wgkgwmcdbi (bmqtjllhgt, rsbidgbpng - xqtaephztp)
-
15 Oct 2019
(500 mg IW-3718 BID)
cluoqncqek(usapfzjqqe) = eqktgivkkp wgkgwmcdbi (bmqtjllhgt, daulksynop - dguxjhpjvk)
Not Applicable
61
(uiuxrliaya) = ngywswehjf gosbgitqkd (ntgijmjdoa, adudketzld - qvgtalngnl)
-
17 Jan 2013
Phase 3
216
(bdwiolazpu) = qkpahstyjo bchfwrsogs (nckuahzwvu )
-
01 Jul 2012
Placebo
(nkfkfaidba) = vgkxwcipdt ruomulvyrx (zbgwuesmru )
Phase 2
24
(Colesevelam)
cvdhljilsc(aqfowizwqq) = cdxxhgchuy crequzibng (eiosxsylnc, tsqyuxbukd - juhivudwzn)
-
15 Mar 2012
Placebo
(Placebo)
cvdhljilsc(aqfowizwqq) = iluhsjsbut crequzibng (eiosxsylnc, caryzitbve - dydvbvvdas)
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Clinical Trial

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Approval

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Regulation

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