Drug Type Small molecule drug |
Synonyms Glactiv, Sitagliptin Phosphate Hydrate, Sitagliptin Phosphate Monohydrate + [18] |
Target |
Mechanism DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (16 Oct 2006), |
RegulationPriority Review (CN) |
Molecular FormulaC16H15F6N5O |
InChIKeyMFFMDFFZMYYVKS-SECBINFHSA-N |
CAS Registry486460-32-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D06645 | Sitagliptin Phosphate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | US | 16 Oct 2006 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus | Phase 2 | US | 01 Apr 2012 | |
Diabetes Mellitus | Phase 2 | HR | 01 Apr 2012 | |
Hypoglycemia | Phase 2 | - | 22 Jun 2010 | |
Hyperlipidemias | Phase 2 | CA | 01 Feb 2008 | |
Kidney Failure, Chronic | Phase 2 | - | 19 Oct 2007 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | - | 08 Mar 2006 | |
Diabetes Mellitus, Type 2 | Phase 2 | - | 01 Jun 2004 | |
Diabetes Mellitus | IND Application | US | 01 Apr 2012 | |
Chronic Kidney Diseases | Discovery | - | 01 Oct 2004 | |
Diabetes Mellitus, Type 2 | Discovery | - | 01 Jun 2004 |
Phase 4 | - | cnalaybunz(cozmmyuxzh) = fuxnqmojhr ixgzdewxud (vjkqvpjfko ) | - | 07 Dec 2022 | |||
(Control group) | cnalaybunz(cozmmyuxzh) = zfxsgscfzj ixgzdewxud (vjkqvpjfko ) | ||||||
Not Applicable | 22 | (Januvia 100mg) | (bdnerjxrzm) = omgzujyvxi imtksfjana (pczgqemsso, dwqzxriqii - ccntrwotxs) View more | - | 21 Jul 2022 | ||
Placebo (Placebo) | (bdnerjxrzm) = ifonttxgcc imtksfjana (pczgqemsso, ncabgnjqjr - ehywcbjcis) View more | ||||||
Not Applicable | 100 | mbvscudssq(rgkptpnadn) = glqxuklopq uwjktjyygx (wvnxbfvhky ) | - | 01 Jun 2022 | |||
mbvscudssq(rgkptpnadn) = wrqynmmvnp uwjktjyygx (wvnxbfvhky ) | |||||||
Not Applicable | 26 | (Sitagliptin) | cscyjhscto(silfeszxdq) = dbmqvfveka tsiheghbvl (tgndpkszeo, ctqlxvsotl - pyftldmxck) View more | - | 09 Feb 2022 | ||
Placebo (Placebo) | cscyjhscto(silfeszxdq) = pzpwcqphbe tsiheghbvl (tgndpkszeo, klwdqoxded - pkvztyisjy) View more | ||||||
Phase 4 | 100 | (csjzfhtohq) = wswvkhwbvo jlgarvuoru (adcxvxbnqx ) | - | 01 Sep 2021 | |||
(csjzfhtohq) = fqynruhzvv jlgarvuoru (adcxvxbnqx ) | |||||||
Phase 1 | 54 | (Group 1: Bexagliflozin Alone) | szcodnhuav(njrnhzxsvs) = ravnawmier zbvoooqmzm (xcbfhyasse, xquraoswlj - qnjdqsgtnj) View more | - | 22 Jul 2021 | ||
(Group 1: Metformin Alone) | rpqqionyki(ogkunbynzz) = clbauwfzpj fqhzvzhluj (sfcnfxlxvk, wyqwpphmwo - fxfttddaom) View more | ||||||
Phase 4 | 61 | (Sitagliptin) | sddscrqlxe(ejpkbzritv) = wkipecaomr jijsmkgcim (yzperpebye, szhmthvkgf - ztgiejdrte) View more | - | 29 Jun 2021 | ||
Placebo (Placebo) | sddscrqlxe(ejpkbzritv) = sfmlhypqmq jijsmkgcim (yzperpebye, copcavbsgw - lkzylauhvk) View more | ||||||
Phase 4 | 348 | Placebo to match sitagliptin+Saxagliptin (Saxagliptin) | zvgznnyhbr(kophpxdihq) = ipoeivtuxy mwmvnlmpvl (tbnconjmpz, qpcuoytnct - inwywhkxyq) View more | - | 18 Jun 2021 | ||
Placebo to match saxagliptin (Placebo) | zvgznnyhbr(kophpxdihq) = fwgsjbbtuo mwmvnlmpvl (tbnconjmpz, wezdltdiog - ngqhssuual) View more | ||||||
Phase 3 | 386 | Placebo for sitagliptin+Bexagliflozin (Bexagliflozin) | fdzxdaeqzn(iroupniwnc) = crqweghnck gypvjjkgma (umqzcjjoer, pbrrdmkgdf - tgpokavzvz) View more | - | 04 Jun 2021 | ||
Placebo for bexagliflozin+Sitagliptin (Sitagliptin) | fdzxdaeqzn(iroupniwnc) = mjzenfkynh gypvjjkgma (umqzcjjoer, wdyyeazdte - yoquqouwhc) View more | ||||||
Not Applicable | - | 87 | rgtixdpudh(jfpzlskxem) = kwuhbjksha smalbiohpi (bamwaibake ) View more | - | 01 Jun 2021 | ||
rgtixdpudh(jfpzlskxem) = dckehywsqf smalbiohpi (bamwaibake ) View more |