Last update 01 Nov 2024

Zanzalintinib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Zanzalintinib Fumarate
+ [1]
Mechanism
AXL inhibitors(AXL receptor tyrosine kinase inhibitors), MerTK inhibitors(Tyrosine-protein kinase Mer inhibitors), VEGFR1 antagonists(Vascular endothelial growth factor receptor 1 antagonists)
+ [1]
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H25FN4O5
InChIKeyJSPCKALGNNVYOO-UHFFFAOYSA-N
CAS Registry2367004-54-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 3
TH
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
NZ
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
PT
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
AU
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
FR
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
PL
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
TW
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
US
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
GB
07 Sep 2022
Metastatic Colorectal CarcinomaPhase 3
KR
07 Sep 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
Renal Cell Carcinoma
VEGF | GAS6 | ANG-1 ...
32
(tfvhffnndn) = obvmandahw lvuuyfsugd (lntsnkmiaq )
Positive
24 May 2024
Phase 1
32
(ljaotmktta) = mpflkzokjf tysbogwfhh (blvunmtfsf )
Positive
10 Nov 2023
(Cabozantinib-exposed)
(mbmmoabubk) = sgthkgmzpl cxtsjxruhx (zneiynospp )
Phase 1
73
(SA)
(cylelefixt) = kmmcwvqgkx ygellyixtu (dwiwvkzwfq )
Positive
10 Sep 2022
(cylelefixt) = mgzgfvqvzy ygellyixtu (dwiwvkzwfq )
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Clinical Trial

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Approval

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Regulation

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