Last update 16 Apr 2025

Candesartan Cilexetil/Hydrochlorothiazide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Atacand HCT, Atacand Plus, Blopress Plus
+ [14]
Action
antagonists, inhibitors
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Austria (03 Nov 1998),
Regulation-
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Structure/Sequence

Molecular FormulaC40H42ClN9O10S2
InChIKeyGBMIVDMAHNBPIH-UHFFFAOYSA-N
CAS Registry1145777-98-5

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
United States
05 Sep 2000
Essential Hypertension
Austria
03 Nov 1998
Essential Hypertension
Belgium
03 Nov 1998
Essential Hypertension
Denmark
03 Nov 1998
Essential Hypertension
Finland
03 Nov 1998
Essential Hypertension
France
03 Nov 1998
Essential Hypertension
Germany
03 Nov 1998
Essential Hypertension
Greece
03 Nov 1998
Essential Hypertension
Ireland
03 Nov 1998
Essential Hypertension
Italy
03 Nov 1998
Essential Hypertension
Luxembourg
03 Nov 1998
Essential Hypertension
Netherlands
03 Nov 1998
Essential Hypertension
Norway
03 Nov 1998
Essential Hypertension
Portugal
03 Nov 1998
Essential Hypertension
Sweden
03 Nov 1998
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
2,207
placebo+candesartan
(Placebo)
stxrobwgnx(gaqnyuwdgn) = vvtqzqfpup fshmdyihhy (xkgqrkkdpz, 0.9)
-
17 Jun 2009
(Candesartan 32 mg)
stxrobwgnx(gaqnyuwdgn) = bomwdmnywr fshmdyihhy (xkgqrkkdpz, 0.4)
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Regulation

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