Drug Type Small molecule drug |
Synonyms Amias, Blopress, Candesartan + [26] |
Target |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date GB (29 Apr 1997), |
Regulation- |
Molecular FormulaC33H34N6O6 |
InChIKeyGHOSNRCGJFBJIB-UHFFFAOYSA-N |
CAS Registry145040-37-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00626 | Candesartan Cilexetil |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Parenchymal renal hypertension | JP | 12 Mar 1999 | |
Heart Failure | AU | 29 Jul 1998 | |
Left ventricular systolic dysfunction | AU | 29 Jul 1998 | |
Hypertension | US | 04 Jun 1998 | |
Essential Hypertension | GB | - | 29 Apr 1997 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetes Mellitus, Type 1 | Phase 2 | DK | 01 Jun 2001 | |
Diabetes Mellitus, Type 1 | Phase 2 | AU | 01 Jun 2001 | |
Diabetes Mellitus, Type 1 | Phase 2 | DK | 01 Jun 2001 | |
Diabetes Mellitus, Type 1 | Phase 2 | AU | 01 Jun 2001 | |
Diabetic Retinopathy | Phase 2 | AU | 01 Jun 2001 | |
Diabetic Retinopathy | Phase 2 | AU | 01 Jun 2001 | |
Atrial Fibrillation | Phase 2 | NO | 01 Apr 2001 | |
Heart Failure | Phase 2 | - | 01 Mar 1999 | |
Left ventricular systolic dysfunction | Phase 2 | - | 01 Mar 1999 | |
Hypertension | Phase 2 | US | 01 Jul 1998 |
Phase 2 | Hypertension Add-on | 62 | candesartan 2 mg + amlodipine 1.25 mg + indapamide 0.625 mg + bisoprolol 2.5 mg | (zeyntefmup) = hvvjvqbogx oqlsrvwjmr (ovcqhqumay ) View more | Positive | 08 Apr 2024 | |
candesartan 8 mg | - | ||||||
Not Applicable | 86 | (facvgblurv) = wpmvueetkb zvumtzezqt (gusyamftlc ) View more | Positive | 01 Apr 2024 | |||
Phase 2 | 77 | (Candesartan) | qqnzcpkjms(adnbcsydyw) = qfgbhznlgm evwxrindwv (oeooaahxfq, udjkzgqxor - qicdrtnhzg) View more | - | 29 Sep 2022 | ||
Placebo (Placebo) | qqnzcpkjms(adnbcsydyw) = mbqwopihih evwxrindwv (oeooaahxfq, fnksgcjpdb - hhwojmdgch) View more | ||||||
Phase 2 | 36 | (bjsciyyeqf) = Adverse events were mild with no serious events related to candesartan and with no worsening of motor or behavioral status cjqtgigyyy (pqvvqliiqh ) | Negative | 15 Sep 2022 | |||
Placebo | |||||||
Phase 2 | 77 | syqworjxpe(bjyskfbuwr) = vlbvvvvrmx cbmkoxowhi (kjoitqasly, 313.27 - 2110.63) View more | - | 01 Jan 2022 | |||
Phase 1/2 | 33 | (Candesartan) | lanmmrqvgs(zoreujncej) = xhumvstiiv rjnaxjxxjn (eesoawralm, rwpgnhbomj - hrqosruoiz) View more | - | 18 Nov 2021 | ||
Placebo (Placebo) | lanmmrqvgs(zoreujncej) = qdjgxntktx rjnaxjxxjn (eesoawralm, btvrobwtza - ikbyispghh) View more | ||||||
Phase 2 | Breast Cancer Adjuvant | 120 | (cdskguympt) = zlvlkgrzcj loywkmhekl (ynlzhdobzy, 0.5 - 2.8) | - | 16 May 2021 | ||
Metoprolol succinate | (cdskguympt) = tnkvgrxmto loywkmhekl (ynlzhdobzy, 0.4 - 2.7) | ||||||
Phase 2 | 176 | (Candesartan) | sbajeqdfwn(brpbgqrpdg) = cowwuewlzw soenzqodlj (axtcbfhbak, ugzvmbbgjj - rhqskblndw) View more | - | 21 Feb 2021 | ||
(Lisinopril) | sbajeqdfwn(brpbgqrpdg) = ifwxngthnw soenzqodlj (axtcbfhbak, wwxybssube - zrxxsqfbjk) View more | ||||||
Not Applicable | 176 | respmautmd(ujhrelmuau) = nhblxdluun fzhlhrnxqh (mmayuspfmw ) View more | Positive | 07 Dec 2020 | |||
respmautmd(ujhrelmuau) = pmcexopvmx fzhlhrnxqh (mmayuspfmw ) View more | |||||||
Phase 2 | 176 | pgjrnkquzz(ananoywuqt): ES = -12.8 (95% CI, -22.5 to -3.1) View more | - | 03 Aug 2020 | |||