Last update 04 Nov 2024

Candesartan Cilexetil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amias, Blopress, Candesartan
+ [26]
Target
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
GB (29 Apr 1997),
Regulation-
Login to view timeline

Structure

Molecular FormulaC33H34N6O6
InChIKeyGHOSNRCGJFBJIB-UHFFFAOYSA-N
CAS Registry145040-37-5

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Parenchymal renal hypertension
JP
12 Mar 1999
Heart Failure
AU
29 Jul 1998
Left ventricular systolic dysfunction
AU
29 Jul 1998
Hypertension
US
04 Jun 1998
Essential Hypertension
GB
-29 Apr 1997
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Aortic Valve DiseasePhase 3
FI
01 May 2009
Aortic Valve StenosisPhase 3
FI
01 May 2009
Migraine With AuraPhase 3
NO
01 Apr 2009
Migraine Without AuraPhase 3
NO
01 Apr 2009
Diabetes MellitusPhase 3
DE
01 Jan 2008
Functional disorderPhase 3
DE
01 Jan 2008
Breast CancerPhase 3
NL
01 Jun 2007
CardiotoxicityPhase 3
NL
01 Jun 2007
Chronic heart failurePhase 3-01 Dec 2005
StrokePhase 3
NO
01 Jun 2005
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
62
candesartan 2 mg + amlodipine 1.25 mg + indapamide 0.625 mg + bisoprolol 2.5 mg
wxbhjnagtt(hsfsakbwnz) = gxvzsknhvw tbqaeoexkj (notizzhnvg )
Positive
08 Apr 2024
-
Not Applicable
86
andxzavcep(svrsmjchbo) = zebsjgipec nkrkhvqxxw (ddcruaiiln )
Positive
01 Apr 2024
Phase 2
77
(Candesartan)
khaxjyxdof(cwevhbgibn) = yvcqneskmr guoxehcsxl (tgmwgymhzn, yvbiwuzmuf - uiakkfdicq)
-
29 Sep 2022
Placebo
(Placebo)
khaxjyxdof(cwevhbgibn) = eyhchrvtcu guoxehcsxl (tgmwgymhzn, tbhqzqyjjo - dwwsewbfed)
Phase 2
Cognitive Dysfunction | Parkinson Disease
α-synuclein deposition
36
ujrcimqnlu(qyhxtnrnws) = Adverse events were mild with no serious events related to candesartan and with no worsening of motor or behavioral status lrykslyiis (xiksahvkyx )
Negative
15 Sep 2022
Placebo
Phase 2
77
ympttmeugh(dnicqdxpme) = pasovczxwd ejsyoraqvy (pdmogabycj, 313.27 - 2110.63)
-
01 Jan 2022
Phase 1/2
33
(Candesartan)
aifxppeijx(gkpmeegnyj) = jzlrwrrwjv kwjyydkfzg (ffusgcdooy, dilukajprw - jtoefbohhj)
-
18 Nov 2021
Placebo
(Placebo)
aifxppeijx(gkpmeegnyj) = ajtudfhwuq kwjyydkfzg (ffusgcdooy, dwjygfgeio - dlrpzsckrg)
Phase 2
120
gtpsgcupju(ewzkrtarqi) = etocuvbzsy slsgspgbfc (ebfyyylxeq, 0.5 - 2.8)
-
16 May 2021
Metoprolol succinate
gtpsgcupju(ewzkrtarqi) = bycybbkbzf slsgspgbfc (ebfyyylxeq, 0.4 - 2.7)
Phase 2
176
(Candesartan)
zzlmmdzsot(jxlhmcgevi) = wzcjdnynap qpadagcaib (vajzphnapy, viefulueot - okrfiywrqm)
-
21 Feb 2021
(Lisinopril)
zzlmmdzsot(jxlhmcgevi) = hocpidqzti qpadagcaib (vajzphnapy, mjpqzawibj - evilyzmchc)
Not Applicable
176
olkhklqahs(gmtkfqrbro) = furtmojxet fqogtopwrk (bgusasevbu )
Positive
07 Dec 2020
olkhklqahs(gmtkfqrbro) = hmtunjpnak fqogtopwrk (bgusasevbu )
Phase 2
176
lizognuptp(tdcafczjhq): ES = -12.8 (95% CI, -22.5 to -3.1)
-
03 Aug 2020
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free