Drug Type Monoclonal antibody |
Synonyms Vibostolimab (USAN), MK-7684 |
Target |
Action inhibitors |
Mechanism TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationOrphan Drug (United States) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-Small Cell Lung Cancer | Phase 3 | United States | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | China | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | Chile | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | Guatemala | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | Russia | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | South Korea | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | Turkey | 07 Apr 2021 | |
Non-Small Cell Lung Cancer | Phase 3 | Ukraine | 07 Apr 2021 | |
Turcot Syndrome | Phase 2 | United States | 15 Jan 2025 | |
Turcot Syndrome | Phase 2 | Taiwan Province | 15 Jan 2025 |
Phase 1/2 | 117 | mkceyujfpj(qjscunqjey) = ybsezgbmgp wttijinvxu (mksooreqmb ) View more | Positive | 14 Sep 2024 | |||
mkceyujfpj(qjscunqjey) = udvqgbyjoa wttijinvxu (mksooreqmb ) View more | |||||||
TIGIT (NEWS) Manual | Phase 2 | - | iruyfzcycr(bdogbimqck) = vxjqnfjsmh sihfchrvqx (bmkolsnhkj ) View more | Negative | 07 Dec 2023 | ||
iruyfzcycr(bdogbimqck) = julopddljm sihfchrvqx (bmkolsnhkj ) View more | |||||||
Phase 1/2 | Melanoma Neoadjuvant | 66 | (arm 1) | uayltpaezs(brkbtlqqgm) = qkqehxnusk ejxejxxymg (xxxayqrgiu ) View more | Positive | 14 Apr 2023 | |
(arm 2) | uayltpaezs(brkbtlqqgm) = okbuqtyrky ejxejxxymg (xxxayqrgiu ) View more | ||||||
Phase 1 | Advanced gastric carcinoma PD-L1-positive | 27 | Vibostolimab 200mg + Pembrolizumab 200mg | ajztvdntiu(acvvlvnlzp) = nnfclfelxt ucgwuhligc (fevrqgrxak ) View more | Positive | 02 Jul 2022 | |
Phase 1 | Uterine Cervical Cancer Third line | 80 | ehumreswvb(kqlkchbvus) = sbkqakszqx zprzdhizoj (dgsvfgomjl ) View more | Positive | 15 Jun 2022 | ||
ehumreswvb(kqlkchbvus) = zohydzleio zprzdhizoj (dgsvfgomjl ) View more | |||||||
Phase 1 | 61 | - | Positive | 15 Jun 2022 | |||
Phase 1 | 41 | sngfhppoks(etgcdebqaf) = xidhxhfkoj ueowwdnvaf (qvswhfsqsl ) View more | Positive | 17 Sep 2020 | |||
Phase 1 | 79 | gafvocigbc(ggtvuglhlm) = jjoadqtabo varujkatyl (naqntwnjbg ) View more | Positive | 17 Sep 2020 | |||
gafvocigbc(ggtvuglhlm) = xmbkgfjfzl varujkatyl (naqntwnjbg ) View more |