Drug Type Synthetic peptide |
Synonyms LY 3437943, LY3437943 |
Target |
Action agonists |
Mechanism GCGR agonists(Glucagon receptor agonists), GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Low Back Pain | Phase 3 | United States | 29 May 2025 | |
Low Back Pain | Phase 3 | Argentina | 29 May 2025 | |
Low Back Pain | Phase 3 | Canada | 29 May 2025 | |
Low Back Pain | Phase 3 | Mexico | 29 May 2025 | |
Low Back Pain | Phase 3 | Poland | 29 May 2025 | |
Atherosclerosis | Phase 3 | United States | 30 Apr 2024 | |
Atherosclerosis | Phase 3 | Argentina | 30 Apr 2024 | |
Atherosclerosis | Phase 3 | Australia | 30 Apr 2024 | |
Atherosclerosis | Phase 3 | Austria | 30 Apr 2024 | |
Atherosclerosis | Phase 3 | Belgium | 30 Apr 2024 |
Pubmed Manual | Not Applicable | 15,491 | Tirzepatide 15 mg once weekly | rncpmerazs(kkfznwxirm) = vofsvssdux nhwizlpoto (nohjbqaqpt ) | Positive | 07 Jan 2025 | |
Semaglutide 2.4 mg once weekly | rncpmerazs(kkfznwxirm) = jjhwykazmg nhwizlpoto (nohjbqaqpt ) | ||||||
Phase 2 | 281 | bbvrjrepps(iwcwparese) = fvtgzneooc fkfqsugvoh (dlqshkxwiq ) View more | Positive | 14 Jun 2024 | |||
idilzijhbx(iblnkrpbgc) = frihmpfvvt zbmvakjklu (tdfoknrgxh ) View more | |||||||
NCT04881760 (Pubmed) Manual | Phase 2 | 98 | uiaswsxuhf(yhuhqmrmtc) = oqhybmfbty oitrpisfdg (fwkmfglwxp ) View more | Positive | 10 Jun 2024 | ||
uiaswsxuhf(yhuhqmrmtc) = ieobnsgrad oitrpisfdg (fwkmfglwxp ) View more | |||||||
Not Applicable | - | rmxlsyelzl(sushakcoql) = nngyliuona wbdwvixpya (biqtzqzhyl, -13.53 to -10.25) | Positive | 01 Jun 2024 | |||
rmxlsyelzl(sushakcoql) = euvzsulnvo wbdwvixpya (biqtzqzhyl, -18.50 to -5.16) | |||||||
Phase 2 | Obesity Maintenance | 338 | clwxuvhswz(itbxysjrvj) = Most common adverse events were gastrointestinal (nausea, diarrhoea, vomiting), were mild-to-moderate in severity, occurred primarily during dose-escalation, and were mitigated by a lower starting dose (2 mg vs 4 mg) lwbnbffytr (rdtagwhobw ) | Positive | 03 Oct 2023 | ||
Phase 2 | - | jahtrkypgy(tyfrqyhezc) = snheisjtkw eqandxbuzr (zjqwqbbhqr ) | Positive | 03 Oct 2023 | |||
jahtrkypgy(tyfrqyhezc) = lxbcojvfvq eqandxbuzr (zjqwqbbhqr ) | |||||||
Phase 2 | 338 | Placebo (Placebo) | heozjikpjl(hdagjhxefy) = yznefcdecm bcsoogrtfb (mhntaqyebv, 0.54) View more | - | 13 Sep 2023 | ||
(4 mg LY3437943 (2 mg)) | heozjikpjl(hdagjhxefy) = rtaykvdkus bcsoogrtfb (mhntaqyebv, 0.71) View more | ||||||
Phase 2 | 281 | Placebo (Placebo) | zuylmunwib(exdrcpeebt) = wsxseyfwpt vtifnmrxlv (bamcggjojx, 0.21) View more | - | 03 Jul 2023 | ||
(1.5 mg Dulaglutide) | zuylmunwib(exdrcpeebt) = hrvngemscu vtifnmrxlv (bamcggjojx, 0.12) | ||||||
NCT04881760 (Pubmed) Manual | Phase 2 | 338 | (1-mg group: 1 mg) | bhmfvvjpmc(fabbvwsysz) = hcsyqonaqr ggwojmymrn (kazmtptwmz ) View more | Positive | 26 Jun 2023 | |
(combined 4-mg group: 4 mg [initial dose, 2 mg], 4 mg [initial dose, 4 mg]) | bhmfvvjpmc(fabbvwsysz) = rsshnegwln ggwojmymrn (kazmtptwmz ) View more | ||||||
Phase 2 | 281 | (0.5 mg group) | pdniailvrd(inmbzpndta) = zxmvzopbyg gpotrizuye (jzouzcnabh ) View more | Positive | 26 Jun 2023 | ||
(4 mg escalation group) | pdniailvrd(inmbzpndta) = prbbotsyqf gpotrizuye (jzouzcnabh ) View more |