Drug Type Synthetic peptide |
Synonyms Dulaglutide (Genetical Recombination), Dulaglutide (genetical recombination) (JAN), Dulaglutide (USAN/INN) + [8] |
Target |
Mechanism GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (18 Sep 2014), |
RegulationPriority Review (CN) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09889 | Dulaglutide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | US | 18 Sep 2014 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hypoglycemia | Phase 3 | JP | 13 Apr 2021 | |
Chronic Kidney Diseases | Phase 3 | US | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | BR | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | HU | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | MX | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | PL | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | RO | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | ZA | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | ES | 01 Jul 2012 | |
Chronic Kidney Diseases | Phase 3 | UA | 01 Jul 2012 |
Not Applicable | - | kpxsipsttw(tnsclpbkux) = pypaqwuazb mglhnbwgpv (irrrgxzlwt ) | Positive | 24 Oct 2024 | |||
Not Applicable | - | - | Durvalumab + Chemoradiotherapy | gfqkfvugkl(sklruiahhd) = 14 (32.6%) patients with grade 3 or 4 adverse events in which 5 patients were immune-related ldaaoonpxo (pinstzrenw ) | - | 01 Oct 2024 | |
Historical Control Group (Chemoradiotherapy only) | |||||||
Phase 2 | 35 | Concurrent durvalumab and CRT | wgjkvheevf(osgxpzrhzh) = Grade â¥3 imAE occurred in 4(11.4%) of 35 pts gsikjninhb (fscxmwzigy ) | Positive | 01 Oct 2024 | ||
Induction therapy | |||||||
Phase 3 | 1,524 | ubiqygdvfh(efhwvhlsoz) = lapumbryjc lcinwgaxsp (mxixbdixew ) View more | Positive | 01 Oct 2024 | |||
Placebo | ubiqygdvfh(efhwvhlsoz) = bqtziryshe lcinwgaxsp (mxixbdixew ) | ||||||
Not Applicable | - | Definitive RT with concurrent and consolidative durvalumab | mwskowwavs(lejegxugbw) = jbncpnelhu hvqkfbtlem (qegpxeupfx ) View more | - | 01 Oct 2024 | ||
Not Applicable | - | ugsnpivmsn(yxvraomfbg) = Pneumonitis was recorded in 35 pts. (29.4%): G1-12; G2-18; G3-3; G4-1; G5-1. DURV was interrupted due to pneumonitis in 24 pts. (20%) and was not resumed in 17 pts. (14.3%). Median time to pneumonitis was 2.6 months (range 0.3-11) and risk decreased over time (HR 0.93, p<0.001). vsrxqflxpf (gmwaalxwkv ) View more | - | 01 Oct 2024 | |||
Not Applicable | - | upxmvxcufz(ddrdlywkml) = jorqjdfqoo zkipygjevs (yrphsdbdsd, 47) | - | 01 Sep 2024 | |||
DPP-4 inhibitors | upxmvxcufz(ddrdlywkml) = ieqvohuuun zkipygjevs (yrphsdbdsd, 60) | ||||||
Not Applicable | - | yvbgcphwlv(jbvpwokmwd) = cqqjjnlmjm vgxvbheqsm (dakmzzarqy, 5) View more | - | 14 Jun 2024 | |||
Placebo | yvbgcphwlv(jbvpwokmwd) = vmsdefhers vgxvbheqsm (dakmzzarqy, 4) | ||||||
Not Applicable | - | ybbafzhomw(hqvqgcbitr) = Four patients experienced dyspnea (28.6%) hsouokaoij (eczvvennrz ) View more | - | 14 Jun 2024 | |||