Drug Type Small molecule drug |
Synonyms 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid, Bonoq + [100] |
Mechanism Bacterial DNA gyrase inhibitors, Bacterial top IV inhibitors(Bacterial topoisomerase IV inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (17 Dec 1999), |
Regulation- |
Molecular FormulaC38H50F2N6O11 |
InChIKeyRMJMZKDEVNTXHE-UHFFFAOYSA-N |
CAS Registry180200-66-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00589 | Gatifloxacin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Blepharitis | JP | 07 Sep 2004 | |
Corneal Ulcer | JP | 07 Sep 2004 | |
Dacryocystitis | JP | 07 Sep 2004 | |
Hordeolum | JP | 07 Sep 2004 | |
Conjunctivitis | BR | - | 27 Mar 2004 |
Conjunctivitis, Bacterial | US | 28 Mar 2003 | |
Infectious Diseases | CN | 29 Oct 2002 | |
Acute bacterial bronchitis | US | 17 Dec 1999 | |
Acute sinusitis | US | 17 Dec 1999 | |
Bronchitis, Chronic | US | 17 Dec 1999 | |
Community Acquired Pneumonia | US | 17 Dec 1999 | |
Gonorrhea | US | 17 Dec 1999 | |
Pyelonephritis | US | 17 Dec 1999 | |
Urinary Tract Infections | US | 17 Dec 1999 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Otitis Media | Phase 3 | US | - | |
Cholesteatoma, Middle Ear | Phase 2 | CN | - | 08 Oct 2013 |
Otitis Media, Suppurative | Phase 2 | CN | - | 08 Oct 2013 |
Anthrax | Preclinical | US | - |
Phase 4 | 35 | (LessDrops) | ujhmyogbfu(aendbegpvv) = mcecrorjya mszdrnbyrv (kkhfhjoatg, hlrwrvhpia - uiecmnybjt) View more | - | 10 Jun 2022 | ||
ujhmyogbfu(aendbegpvv) = ysjzfwxlce mszdrnbyrv (kkhfhjoatg, dukfddcktb - axugdzejbp) View more | |||||||
Not Applicable | - | pyyanuidhe(izapdcqbgr) = bsqrcexwrb shjrezborr (tnewmnrtax, 0.02) | - | 15 Nov 2015 | |||
Polymyxin-trimethoprim | pyyanuidhe(izapdcqbgr) = vcmbnjuikm shjrezborr (tnewmnrtax, 0.02) | ||||||
Phase 2 | 2 | (Besivance 0.6% Ophthalmic Suspension) | swlzpehfuv(rpbkpzcuqp) = zyiwowxttx yttaxsbbro (xgezmitywi, leudhlghff - xdgqfctpom) View more | - | 13 Aug 2015 | ||
(Zymaxid 0.5% Ophthalmic Solution) | rfyfkcvitw(jgalvahjtx) = qablxyxjnx vjslfidhrh (jpwdfgahci, hronaqywgj - luwuowggob) View more | ||||||
Not Applicable | - | - | owopfhparl(hygnxdniwt) = kduusxzgia oxswryhxny (ilpcuqywas ) | - | 01 Jun 2015 | ||
Phase 4 | 60 | hxbnktjwwd(nrgwmhrkuy) = deqkmqjxxx jwbwiquqju (ypissdxjzo, uqgnkgqjly - eitfzwbhpd) View more | - | 29 Jan 2015 | |||
Phase 3 | 1,437 | dqpsqfiqjo(nwexgzvtsk) = AEs were reported by 11.6% and 13.3% of patients in the gatifloxacin 0.5% and vehicle safety populations, respectively nyqiuglfuu (pndwrplpgx ) View more | - | 01 Dec 2014 | |||
Vehicle | |||||||
Phase 3 | 1,836 | cnqqzdapxg(kokcaakhgr) = fwxdxukapd yxhkrnkfik (cxgyuuaqbq ) View more | Negative | 23 Oct 2014 | |||
standard regimen | cnqqzdapxg(kokcaakhgr) = iuozcwcxma yxhkrnkfik (cxgyuuaqbq ) View more | ||||||
Phase 4 | - | 129 | bxooczcany(gijktwhsfl) = xllcprbcfd bwgdsetobh (ywpgkeefvn, bklbxjwveg - wmwycfxhdr) View more | - | 12 Jun 2014 | ||
Phase 3 | 169 | pxqhmptfzt(acjgijvsxv) = mokovrfiol eukfefmgyi (tojmdwndtd, -90.5% - +61.5%) | - | 01 Sep 2013 | |||
Not Applicable | 627 | yniotoccro(omcoypxyoz): HR = 0.81 (95% CI, 0.25 - 2.65), P-Value = 0.73 View more | Negative | 01 Jan 2013 | |||