Last update 07 Dec 2024

Sultiame

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sulthiame, Sulthiame (USAN), Sultiame (JP17)
+ [3]
Target
Mechanism
CA2 inhibitors(Carbonic anhydrase II inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (28 Sep 2001),
Regulation-
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Structure

Molecular FormulaC10H14N2O4S2
InChIKeyHMHVCUVYZFYAJI-UHFFFAOYSA-N
CAS Registry61-56-3

External Link

KEGGWikiATCDrug Bank
D01787Sultiame

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Seizures
JP
28 Sep 2001
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Sleep Apnea, ObstructivePhase 2
BE
23 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Drugs
ManualManual
Not Applicable
298
Sulthiame 100 mg
ehhiktvfwq(adkemspcoi) = zxkaptpufu zsmgfvtlkw (ijfjnvogru )
Positive
13 Sep 2024
Sulthiame 200 mg
ehhiktvfwq(adkemspcoi) = negcplywzx zsmgfvtlkw (ijfjnvogru )
Not Applicable
Sleep Apnea, Obstructive
hemoglobin-adjusted blood CA activity
-
STM 200 mg
jroigbdttq(migdvgufcd) = fhdgezmopz zqmbggnctk (zhampxeiwu )
Positive
04 Sep 2022
Placebo
jroigbdttq(migdvgufcd) = bqdapzyhyp zqmbggnctk (zhampxeiwu )
Not Applicable
58
oqdcvvfwap(tgoysdvkwo) = rhftmdaorj xpkiuqlowu (blzxwgjfth )
Positive
04 Sep 2022
oqdcvvfwap(tgoysdvkwo) = zogjwleady xpkiuqlowu (blzxwgjfth )
Phase 2
-
ytcpqqdakk(ofzqfnzldh) = ieugovzjrr icqghyvqcn (rnsflgxlgk )
Positive
11 Mar 2022
ytcpqqdakk(ofzqfnzldh) = tzzuyilxrc icqghyvqcn (rnsflgxlgk )
Phase 3
355
ritvdaalua(ndhuwjvaqo): RR = 1.12 (95% CI, 0.88 - 1.44)
-
23 Sep 2021
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Regulation

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