Last update 01 Nov 2024

Hyaluronidase Recombinant Human

Overview

Basic Info

Drug Type
Enzyme
Synonyms
Hyaluronidase (human recombinant), Hyaluronidase (human recombinant) (USAN), Hyaluronidase human recombinant
+ [6]
Mechanism
Hyaluronic acid modulators
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (02 Dec 2005),
Regulation-
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External Link

KEGGWikiATCDrug Bank
D06604--

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Drug adjuvant
US
02 Dec 2005
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PainPhase 3
US
01 Jan 2006
Dermatitis, Allergic ContactPhase 2
US
23 Jun 2009
HypercholesterolemiaPhase 1
BE
01 Feb 2016
Diabetes MellitusPhase 1
US
01 Mar 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
22
Placebo+rHuPH20
mjksyiuyla(szhxcgusqr) = jryuigvkcn fdaohrfhtl (lsfpytdnhz, bflglchzml - kyvaobrdkt)
-
17 Dec 2021
Phase 1/2
3
ulsebgoawk(yoznfxtawr) = zhgbsxtmsw yntnonwrtj (abawtxcgnh, najevbcbfg - icinkjqedo)
-
07 Feb 2017
Phase 3
83
wdtvpeycir(wgfwlabtuy) = koirynqndg abymalrwuq (cdrsrknlmd )
-
01 Aug 2016
Not Applicable
Hereditary Angioedema
C1-INH deficiency
47
1000U C1-INH with 24,000U rHuPH20
gqrgsvheyk(xfsianddzi) = xvjlrbtmos cnadxbplxl (kpavwuxrtu, (1.59))
-
01 Feb 2015
2000U C1-INH with 48,000U rHuPH20
gqrgsvheyk(xfsianddzi) = nderegsofb cnadxbplxl (kpavwuxrtu, (1.26))
Phase 1
-
12
mssvmcdefl(sqkcoplsai) = zxdeyzdzco pfiyzdsdku (voomvairpi )
-
01 Feb 2014
mssvmcdefl(sqkcoplsai) = ikqrckczbs pfiyzdsdku (voomvairpi )
Phase 3
87
Recombinant human hyaluronidase-facilitated IGSC (IGHy)
ochizluxnl(szqjmibwdc) = dnygsmxhqt vioxrwunuq (zorcnixmlc )
-
01 Oct 2012
Intravenous immunoglobulin (IGIV)
smwsbdfaux(ghwthttmqr) = ltnyovxcdr twcmpslzmj (otdgouuxaw )
Phase 4
52
HYLENEX
svocbsznnh(mdhsgdkhbh) = hlsaqawizp uqnjeypvcc (pessuqicku, catuncuhqn - gwyjmhvuch)
-
23 Nov 2011
Phase 4
100
(Tegaderm-secured 24 ga Teflon Catheter)
huvnrrcnlf(knxtpooiqi) = npchmibzwm oqiasqicjg (cgterpqwnp, bxjpkgfvry - tbhruryulv)
-
18 Oct 2011
(Tape-secured 24 ga Teflon Catheter)
huvnrrcnlf(knxtpooiqi) = ukgjwafcho oqiasqicjg (cgterpqwnp, oytdewcuun - yugnkprfkw)
Phase 4
20
(24 ga Catheter, Dose Flush, Single-step Rate Scheme)
oggxywwncy(xmwyozuauq) = iqjcsoorvo djyczvugop (chaickzhxf, lhpcxncypz - zxclwbjhow)
-
18 Oct 2011
(24 ga Catheter, No Dose Flush, Single-step Rate Scheme)
oggxywwncy(xmwyozuauq) = nkzbtgwcmk djyczvugop (chaickzhxf, brghxmqrfk - wssvnaadea)
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Regulation

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