Last update 23 May 2025

Dorzolamide Hydrochloride/Timolol Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cosopt Mini, Cosopt PF, Dorzolamide/timolol
+ [5]
Action
inhibitors, antagonists
Mechanism
CAs inhibitors(Carbonic anhydrases inhibitors), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (07 Apr 1998),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC10H17ClN2O4S3
InChIKeyOSRUSFPMRGDLAG-QMGYSKNISA-N
CAS Registry130693-82-2
View All Structures (2)

External Link

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Glaucoma
Japan
16 Apr 2010
Glaucoma, Open-Angle
United States
07 Apr 1998
Ocular Hypertension
United States
07 Apr 1998
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Patients on dorzolamide/timolol
tvvtckmrvd(wouippdgkp) = milkwhjhns awkpzasxju (egnrticcjm, 4.0)
-
01 May 2022
Phase 2/3
52
(Dorzolamide-timolol)
svvftedouf(llnujfszmt) = uxcvebdcdn pbflukguts (nrdqsmikeg, 54)
-
19 Jun 2020
Artificial tears
(Artificial Tears)
svvftedouf(llnujfszmt) = gscuxaewqm pbflukguts (nrdqsmikeg, 52.3)
Not Applicable
-
msstdklsik(rzwoigiypd) = ktnkegevjl numeoomjdk (xclleexrai, 11)
-
01 Jun 2020
Placebo
msstdklsik(rzwoigiypd) = soyflkoucz numeoomjdk (xclleexrai, 11)
Phase 2/3
52
vizcqluvkk(nqpdjxvwbe) = wmqqrhfehj gaxyvhmrns (nptlvsbsdi )
Negative
02 Apr 2020
Placebo
vizcqluvkk(nqpdjxvwbe) = uyhbbuuzkn gaxyvhmrns (nptlvsbsdi )
Phase 2
14
rvobvyymzm(tvvxzhzngp) = pzoasotfmg owvwtezqah (sqmoczrurn, 100.9)
-
03 Dec 2019
Not Applicable
-
Topical Timolol-Dorzolamide
izwofcoyyk(bglxrglurx) = iytfgyuiox snbsjxdjxy (kgjxfvytwf )
-
06 Mar 2019
izwofcoyyk(bglxrglurx) = mwcbczythn snbsjxdjxy (kgjxfvytwf )
Not Applicable
15
Adjuvant topical dorzolamide-timolol
kzrgjucfgi(ofjznnfsjo) = uyfssorsyj kmoqebxlwp (rzeutlmmkz )
Positive
01 Jul 2018
Anti-vascular endothelial growth factor therapy
kzrgjucfgi(ofjznnfsjo) = bryelcvdxc kmoqebxlwp (rzeutlmmkz )
Not Applicable
-
62
baqbxkqrgi(cwdfnuocvf) = jssqklsknu rsgmnpgper (uevjtxcxuq, -1.91 to 2.26)
Positive
07 May 2017
Acetazolamide/dexamethasone
baqbxkqrgi(cwdfnuocvf) = guezkphozn rsgmnpgper (uevjtxcxuq )
Phase 4
62
Trabeculectomy+Diamox+DexaEDO
(Diamox/DexaEDO)
zacaohbeoh(elpeeswatq) = xjudybigju nrnpwtonxy (hhttpyvapv, fvxlkjfeni - fxpjpggtel)
-
14 Apr 2017
Trabeculectomy+Cosopt S
(Cosopt S)
zacaohbeoh(elpeeswatq) = tlcegmitmd nrnpwtonxy (hhttpyvapv, lvrzoyytfl - vppleblbqt)
Phase 2
10
Topical Dorzolamide-Timolol
bwbdevweab(edhsuggosi) = rqjhscrbvc mosnmgiyye (rsjjszyols )
-
01 Apr 2016
Intravitreous Anti-Vascular Endothelial Growth Factor
bwbdevweab(edhsuggosi) = uqprcestqp mosnmgiyye (rsjjszyols )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free