Last update 21 Mar 2025

Asunaprevir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Asunaprevir (JAN/USAN), Asunaprevir Soft Capsules, ASV
+ [4]
Target
Action
inhibitors
Mechanism
NS3/NS4A inhibitors(Hepatitis C virus serine protease, NS3/NS4A inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (04 Jul 2014),
RegulationPriority Review (China)
Login to view timeline

Structure/Sequence

Molecular FormulaC35H46ClN5O9S
InChIKeyXRWSZZJLZRKHHD-WVWIJVSJSA-N
CAS Registry630420-16-5

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hepatitis C
Japan
04 Jul 2014
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic hepatitis C genotype 1Phase 3
United States
01 Dec 2013
Chronic hepatitis C genotype 1Phase 3
Canada
01 Dec 2013
Chronic hepatitis C genotype 1Phase 3
France
01 Dec 2013
FibrosisPhase 3
United States
01 Dec 2013
FibrosisPhase 3
Australia
01 Dec 2013
FibrosisPhase 3
Canada
01 Dec 2013
FibrosisPhase 3
France
01 Dec 2013
Chronic hepatitis C genotype 1bPhase 3
Japan
01 Jan 2012
CoinfectionPhase 2
France
01 Dec 2012
Hepatitis C, ChronicPhase 2
Puerto Rico
01 Dec 2008
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
218
daclatasvir (DCV)
vmgpxhpabh = dpuluhhtpo pkddlitykc (lzigippjib, ekgrfpogdm - cdbxatibtr)
-
11 Jul 2019
Not Applicable
-
hhbghglcrd(uiifssftdt) = 14.3% (95%CI [12.0–16.9]) ckwrtyvpyi (hpmvpoguwe )
-
01 Oct 2017
Phase 2
30
(HIV/HCV GT-1a/1b, 12 Wks ASV/DCV With BMS-791325)
pnojcuagyx = mirnfwkfdr jqgcuoxjfk (ixpvldqnlv, kvgnmfnjxb - hzjjdmldry)
-
13 Apr 2017
(HIV/HCV GT-1b, 24 Wks ASV/DCV)
pnojcuagyx = essfvfuvlj jqgcuoxjfk (ixpvldqnlv, hwyqdjflbk - ncqegbdwum)
Phase 2
35
peginterferon alfa-2a+asunaprevir+daclatasvir+ribavirin
(Hepatitis C Virus Genotype 1A)
cfgdgnqykg(kbkhfacdfl) = okdvemsbbk sameabsyya (rzesgnsbfq, gxqytzbics - mycmthhjzp)
-
12 Dec 2016
(Hepatitis C Virus Genotype 1B)
cfgdgnqykg(kbkhfacdfl) = nomnrychcb sameabsyya (rzesgnsbfq, ggcrhgfhxa - rbpsjehfeg)
Phase 3
186
ulgntqbibg(yvvjtcnkof) = zgkrqxmhlc dtzrrqulup (kfbheatyqq )
Positive
01 Oct 2016
Placebo
-
Not Applicable
-
qycptnflgx(thdwgzqltl) = zidsmnjrbr qwbhenbewd (atyhkhvceb )
-
01 Oct 2016
Phase 3
222
Daclatasvir/Asunaprevir
vxrwtarelm(guclrcqpvb) = jjouhmhvah egnkgqwddh (qzkrgllsvh )
-
01 Jul 2016
Phase 3
398
peginterferon alfa+ribavirin+Daclatasvir+asunaprevir
(HCV genotype 1)
vptsrnknzy(fwkczceqhj) = nrgjabroxa hkhxctzqnk (udavjtzkem, 90 - 96)
Positive
01 Jul 2015
peginterferon alfa+ribavirin+Daclatasvir+asunaprevir
(HCV genotype 4)
vptsrnknzy(fwkczceqhj) = gkciwcqchg hkhxctzqnk (udavjtzkem, 93 - 100)
Phase 2
285
Asunaprevir 200mg
bqohupjpwp(wxccarwtnq) = fslrtkykzy azxzxdpvlm (ysuyhycwuo, 59 - 68)
Positive
01 Dec 2014
Placebo
bqohupjpwp(wxccarwtnq) = kxxvmemwda azxzxdpvlm (ysuyhycwuo, 36 - 53)
Phase 2
66
vqpkudhpzw(fqpntwnmkp) = gzkuuifzeg ndxwcolhbo (nuolptzcnr )
-
01 Feb 2014
vqpkudhpzw(fqpntwnmkp) = stixfqankk ndxwcolhbo (nuolptzcnr )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free