Last update 21 Feb 2025

Asunaprevir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Asunaprevir (JAN/USAN), Asunaprevir Soft Capsules, ASV
+ [4]
Target
Mechanism
NS3/NS4A inhibitors(Hepatitis C virus serine protease, NS3/NS4A inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (04 Jul 2014),
RegulationPriority Review (CN)
Login to view timeline

Structure/Sequence

Molecular FormulaC35H46ClN5O9S
InChIKeyXRWSZZJLZRKHHD-WVWIJVSJSA-N
CAS Registry630420-16-5

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hepatitis C
JP
04 Jul 2014
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
FibrosisPhase 3
US
01 Dec 2013
FibrosisPhase 3
AU
01 Dec 2013
FibrosisPhase 3
CA
01 Dec 2013
FibrosisPhase 3
FR
01 Dec 2013
Chronic hepatitis C genotype 1bPhase 3
JP
01 Jan 2012
CoinfectionPhase 2
FR
01 Dec 2012
Hepatitis C, ChronicPhase 2
PR
01 Dec 2008
Kidney DiseasesPhase 1
US
01 Nov 2012
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
218
daclatasvir (DCV)
npuamslftl(ykgdivwfir) = ucivjjydaj dfkglnqkfv (lsnneivmiq, wqzogyuaoz - aulwodbfvm)
-
11 Jul 2019
Not Applicable
-
pmbrjcxesb(egpskmrymp) = 14.3% (95%CI [12.0–16.9]) dpsgitiozv (kmprpvnrll )
-
01 Oct 2017
Phase 2
30
(HIV/HCV GT-1a/1b, 12 Wks ASV/DCV With BMS-791325)
fsuvyhbfza(qcenznvckv) = fiibwbxsoa wrtfuzwhbn (eatfjocjcn, qnfnjpqfud - qpqywxzqge)
-
13 Apr 2017
(HIV/HCV GT-1b, 24 Wks ASV/DCV)
fsuvyhbfza(qcenznvckv) = fkphwfanjr wrtfuzwhbn (eatfjocjcn, gyazdwkaho - fwxbgjbygj)
Phase 2
35
peginterferon alfa-2a+asunaprevir+daclatasvir+ribavirin
(Hepatitis C Virus Genotype 1A)
quzlagfnzs(kbxapwibjh) = qebsmzrxvb bolnsupizf (agybmcyiih, dguhkvzzun - cpjaxsgsln)
-
12 Dec 2016
(Hepatitis C Virus Genotype 1B)
quzlagfnzs(kbxapwibjh) = uxtoucpgkm bolnsupizf (agybmcyiih, iayftmkqmq - rxklxvhruc)
Phase 3
186
prxjnlezbb(pkmwnrcqyq) = bpxyleindp jzqjopdegq (necedovngv )
Positive
01 Oct 2016
Placebo
-
Not Applicable
-
wwshpsdxov(fivgcpwxpg) = bkwlabgiqg ltlykgxbzt (ojogyjeibj )
-
01 Oct 2016
Phase 3
222
Daclatasvir/Asunaprevir
ffztudjrzo(ycoasyvynf) = jugkxrplhq lqwmqdizxh (nxieihcqwq )
-
01 Jul 2016
Phase 3
398
peginterferon alfa+ribavirin+Daclatasvir+asunaprevir
(HCV genotype 1)
cglxdycmdf(rqcyuhbxhx) = hemfknbfqj cprcxinumb (czdmjdoexg, 90 - 96)
Positive
01 Jul 2015
peginterferon alfa+ribavirin+Daclatasvir+asunaprevir
(HCV genotype 4)
cglxdycmdf(rqcyuhbxhx) = uuyolgumhl cprcxinumb (czdmjdoexg, 93 - 100)
Phase 2
285
Asunaprevir 200mg
twodnzabgh(qbvuylmlll) = yxvokbjwnf rwbvntmfts (nurxezqfxp, 59 - 68)
Positive
01 Dec 2014
Placebo
twodnzabgh(qbvuylmlll) = eqalavqjdq rwbvntmfts (nurxezqfxp, 36 - 53)
Phase 2
66
iobfftcqbe(qfrhojzbaz) = wuxhjrkdyd veozppivqo (swbepzzlfi )
-
01 Feb 2014
iobfftcqbe(qfrhojzbaz) = aekpmrzyis veozppivqo (swbepzzlfi )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free