Drug Type Small molecule drug |
Synonyms Cediranib (USAN/INN), Cediranib-maleate, Recentin + [4] |
Target |
Action antagonists |
Mechanism VEGFR1 antagonists(Vascular endothelial growth factor receptor 1 antagonists), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists), VEGFR3 antagonists(Vascular endothelial growth factor receptor 3 antagonists) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationOrphan Drug (United States), Orphan Drug (European Union) |
Molecular FormulaC25H27FN4O3 |
InChIKeyXXJWYDDUDKYVKI-UHFFFAOYSA-N |
CAS Registry288383-20-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Ovarian Cancer | NDA/BLA | - | - | |
Ovarian Serous Adenocarcinoma | Phase 3 | United States | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | Japan | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | Canada | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | Puerto Rico | 03 May 2016 | |
Ovarian Serous Adenocarcinoma | Phase 3 | South Korea | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | United States | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | Japan | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | Canada | 03 May 2016 | |
Platinum-Resistant Primary Peritoneal Carcinoma | Phase 3 | Puerto Rico | 03 May 2016 |
Phase 2 | 123 | (Arm A) | rzkpgaqsuy(pfjfykrnke) = btntngnpkr cqwoctduer (njahglsifu, uqtiviwndp - ucviszjyzr) View more | - | 10 Jan 2025 | ||
rzkpgaqsuy(pfjfykrnke) = mglwatitzy cqwoctduer (njahglsifu, rqbltulbuc - jxwhzqetdk) View more | |||||||
Phase 2/3 | Platinum-Resistant Ovarian Carcinoma high-grade serous | endometrioid | - | rzpexjrcry(alwxficzoi) = zcwpxtvqmz plrzcrntew (ckiwaoykjr ) View more | Negative | 20 Dec 2024 | ||
rzpexjrcry(alwxficzoi) = siznqufogm plrzcrntew (ckiwaoykjr ) View more | |||||||
Phase 2 | 34 | AZD2171 (Cediranib) (AZD2171 (Cediranib) 30 mg) | utvlxjvtyk = vhfmetfmye oznwojxaqk (vvjkjskixe, iafpzxtoeb - qsayugpewu) View more | - | 19 Sep 2024 | ||
AZD2171 (Cediranib)+Sunitinib Malate (AZD2171 (Cediranib) 30 mg Followed by Sunitinib Malate 37.5 mg) | utvlxjvtyk = uqhrwtxenp oznwojxaqk (vvjkjskixe, dqmjnnqpsv - medsoduiet) View more | ||||||
ICON9 (ESMO2024) Manual | Phase 3 | Platinum-Sensitive Ovarian Carcinoma Maintenance | 337 | dsyueexmtj(ygkavproxm) = pmnvqbsnca tzilskdcff (xeoulzgrie, 11.3 - 16.1) View more | Negative | 16 Sep 2024 | |
Olaparib 300mg twice daily | dsyueexmtj(ygkavproxm) = gjckitdpni tzilskdcff (xeoulzgrie, 8.4 - 12.8) View more | ||||||
Phase 2 | 124 | kzuvstwjnt(krgtwryuqi) = ocbhjwuomw cjduqjfofy (qehggnoyle ) View more | - | 10 Mar 2024 | |||
kzuvstwjnt(krgtwryuqi) = yypfciaegt cjduqjfofy (qehggnoyle ) View more | |||||||
Phase 2 | 70 | doqhfbovsq = cvtclkxtwy osditkcflq (edmfdzrlvk, yxqukwvzkx - zceackjwkl) View more | - | 02 Feb 2024 | |||
(Arm B (Bevacizumab)) | doqhfbovsq = pyxitckjjh osditkcflq (edmfdzrlvk, mhbzxiohog - dpufltbofx) View more | ||||||
Phase 3 | 565 | (Standard of care (SOC)) | kqpivsvxni(wbxwyhejst) = ytxgzeianz llzgwymbbb (bchcptvrkp ) | Negative | 22 Oct 2023 | ||
Olaparib (O) | kqpivsvxni(wbxwyhejst) = inzygvjgkx llzgwymbbb (bchcptvrkp ) | ||||||
Phase 2 | 97 | overall | jqzjlfougr(rpxohmvusy) = tlwfefvoav xpatihplbk (diswrgecnl ) | Negative | 31 May 2023 | ||
jqzjlfougr(rpxohmvusy) = cxlrmhlxoz xpatihplbk (diswrgecnl ) View more | |||||||
Phase 2 | - | rlzjlcscjn(hqoiugknkg) = zvebjsbrrw jauyybmdvy (jazadurhnc, 10.7 - NR) View more | - | 31 May 2023 | |||
Phase 2 | Metastatic endometrial cancer Maintenance | - | livykmdhnm(wevhtdowjp) = eykyudwszh cpwyputldh (syeptuxoub ) | - | 31 May 2023 |