Last update 27 Mar 2025

Cediranib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cediranib (USAN/INN), Cediranib-maleate, Recentin
+ [4]
Action
antagonists
Mechanism
VEGFR1 antagonists(Vascular endothelial growth factor receptor 1 antagonists), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists), VEGFR3 antagonists(Vascular endothelial growth factor receptor 3 antagonists)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union)
Login to view timeline

Structure/Sequence

Molecular FormulaC25H27FN4O3
InChIKeyXXJWYDDUDKYVKI-UHFFFAOYSA-N
CAS Registry288383-20-0

External Link

KEGGWikiATCDrug Bank
D08881Cediranib

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Ovarian CancerNDA/BLA--
Ovarian Serous AdenocarcinomaPhase 3
United States
03 May 2016
Ovarian Serous AdenocarcinomaPhase 3
Japan
03 May 2016
Ovarian Serous AdenocarcinomaPhase 3
Canada
03 May 2016
Ovarian Serous AdenocarcinomaPhase 3
Puerto Rico
03 May 2016
Ovarian Serous AdenocarcinomaPhase 3
South Korea
03 May 2016
Platinum-Resistant Primary Peritoneal CarcinomaPhase 3
United States
03 May 2016
Platinum-Resistant Primary Peritoneal CarcinomaPhase 3
Japan
03 May 2016
Platinum-Resistant Primary Peritoneal CarcinomaPhase 3
Canada
03 May 2016
Platinum-Resistant Primary Peritoneal CarcinomaPhase 3
Puerto Rico
03 May 2016
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
123
(Arm A)
rzkpgaqsuy(pfjfykrnke) = btntngnpkr cqwoctduer (njahglsifu, uqtiviwndp - ucviszjyzr)
-
10 Jan 2025
rzkpgaqsuy(pfjfykrnke) = mglwatitzy cqwoctduer (njahglsifu, rqbltulbuc - jxwhzqetdk)
Phase 2/3
Platinum-Resistant Ovarian Carcinoma
high-grade serous | endometrioid
-
rzpexjrcry(alwxficzoi) = zcwpxtvqmz plrzcrntew (ckiwaoykjr )
Negative
20 Dec 2024
rzpexjrcry(alwxficzoi) = siznqufogm plrzcrntew (ckiwaoykjr )
Phase 2
34
AZD2171 (Cediranib)
(AZD2171 (Cediranib) 30 mg)
utvlxjvtyk = vhfmetfmye oznwojxaqk (vvjkjskixe, iafpzxtoeb - qsayugpewu)
-
19 Sep 2024
AZD2171 (Cediranib)+Sunitinib Malate
(AZD2171 (Cediranib) 30 mg Followed by Sunitinib Malate 37.5 mg)
utvlxjvtyk = uqhrwtxenp oznwojxaqk (vvjkjskixe, dqmjnnqpsv - medsoduiet)
Phase 3
337
Olaparib 300mg twice daily + Cediranib 20mg once daily
dsyueexmtj(ygkavproxm) = pmnvqbsnca tzilskdcff (xeoulzgrie, 11.3 - 16.1)
Negative
16 Sep 2024
Olaparib 300mg twice daily
dsyueexmtj(ygkavproxm) = gjckitdpni tzilskdcff (xeoulzgrie, 8.4 - 12.8)
Phase 2
124
kzuvstwjnt(krgtwryuqi) = ocbhjwuomw cjduqjfofy (qehggnoyle )
-
10 Mar 2024
kzuvstwjnt(krgtwryuqi) = yypfciaegt cjduqjfofy (qehggnoyle )
Phase 2
70
(Arm A (Olaparib, Cediranib Maleate))
doqhfbovsq = cvtclkxtwy osditkcflq (edmfdzrlvk, yxqukwvzkx - zceackjwkl)
-
02 Feb 2024
(Arm B (Bevacizumab))
doqhfbovsq = pyxitckjjh osditkcflq (edmfdzrlvk, mhbzxiohog - dpufltbofx)
Phase 3
565
(Standard of care (SOC))
kqpivsvxni(wbxwyhejst) = ytxgzeianz llzgwymbbb (bchcptvrkp )
Negative
22 Oct 2023
Olaparib (O)
kqpivsvxni(wbxwyhejst) = inzygvjgkx llzgwymbbb (bchcptvrkp )
Phase 2
97
overall
jqzjlfougr(rpxohmvusy) = tlwfefvoav xpatihplbk (diswrgecnl )
Negative
31 May 2023
Cediranib or Cediranib + Olaparib
(IL-6 > 4 pg/ml)
jqzjlfougr(rpxohmvusy) = cxlrmhlxoz xpatihplbk (diswrgecnl )
Phase 2
-
rlzjlcscjn(hqoiugknkg) = zvebjsbrrw jauyybmdvy (jazadurhnc, 10.7 - NR)
-
31 May 2023
Phase 2
-
livykmdhnm(wevhtdowjp) = eykyudwszh cpwyputldh (syeptuxoub )
-
31 May 2023
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free